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Dose Escalation Study of Intravitreal 4D-110 in Patients With Choroideremia

Choroideremia Clinical Trial

Official title:
Phase 1 Open-Label, Dose-Escalation Study of the Safety, Tolerability and Preliminary Efficacy of Intravitreal 4D-110 in Patients With Choroideremia

Clinical Trial Summary

This study will evaluate safety, tolerability, and preliminary efficacy of a single intravitreal (IVT) injection of a recombinant adeno-associated virus (AAV) gene therapy, 4D-110, in male patients with genetically-confirmed Choroideremia (CHM).

Clinical Trial Description

This is an open-label, Phase 1 study to evaluate safety and tolerability as well as preliminary efficacy of a single IVT injection of 4D-110 at two dose levels in male patients with genetically-confirmed CHM. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04483440
Study type Interventional
Source 4D Molecular Therapeutics
Contact
Status Active, not recruiting
Phase Phase 1
Start date June 2, 2020
Completion date June 2027
View Details
See also
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