Choroideremia Clinical Trial
Official title:
Natural History of the Progression of Choroideremia Study
The objective of this natural history study is to gain a better understanding of the progression of choroideremia (CHM) and add to the knowledge base for this rare disease.
This study was previously posted by NightstaRx Ltd. In October 2020, sponsorship of the trial was transferred to Biogen. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT02553135 -
Choroideremia Gene Therapy Clinical Trial
|
Phase 2 | |
| Completed |
NCT01461213 -
Gene Therapy for Blindness Caused by Choroideremia
|
Phase 1/Phase 2 | |
| Completed |
NCT03507686 -
A Safety Study of Retinal Gene Therapy for Choroideremia With Administration of BIIB111
|
Phase 2 | |
| Recruiting |
NCT05258032 -
Structural and Functional Characterization of Rare Ocular Diseases
|
||
| Recruiting |
NCT05282953 -
A Phase I/II Dose-escalating Study of the Safety, Tolerability and Efficacy of KIO-301 Administered Intravitreally to Patients With Retinitis Pigmentosa and Choroideremia (ABACUS)
|
Phase 1/Phase 2 | |
| Withdrawn |
NCT05045703 -
The Dark-Adapted Retinal Function Response in Choroideremia (DARC) Study
|
N/A | |
| Recruiting |
NCT01866371 -
High Resolution Retinal Imaging
|
||
| Completed |
NCT01603576 -
Pilot Study of a Suprachoroidal Retinal Prosthesis
|
N/A | |
| Enrolling by invitation |
NCT03584165 -
Long-term Safety and Efficacy Follow-up of BIIB111 for the Treatment of Choroideremia and BIIB112 for the Treatment of X-Linked Retinitis Pigmentosa
|
Phase 3 | |
| Recruiting |
NCT02435940 -
Inherited Retinal Degenerative Disease Registry
|
||
| Active, not recruiting |
NCT04483440 -
Dose Escalation Study of Intravitreal 4D-110 in Patients With Choroideremia
|
Phase 1 | |
| Completed |
NCT02671539 -
THOR - Tübingen Choroideremia Gene Therapy Trial
|
Phase 2 | |
| Completed |
NCT02670980 -
Compensation for Blindness With the Intelligent Retinal Implant System (IRIS V2) in Patients With Retinal Dystrophy
|
N/A | |
| Completed |
NCT02341807 -
Safety and Dose-escalation Study of AAV2-hCHM in Participants With CHM (Choroideremia) Gene Mutations
|
Phase 1/Phase 2 | |
| Completed |
NCT03406416 -
Study of a Suprachoroidal Retinal Prosthesis
|
N/A | |
| Enrolling by invitation |
NCT05158049 -
Longitudinal Study of a Bionic Eye
|
||
| Terminated |
NCT02994368 -
"Natural History" Study of Choroideremia
|
||
| Terminated |
NCT01654562 -
The Short-term Effects of Simvastatin on the Vision of Males Affected by Choroideremia
|
Phase 1/Phase 2 | |
| Active, not recruiting |
NCT00427180 -
IRIS PILOT - Extended Pilot Study With a Retinal Implant System
|
N/A | |
| Completed |
NCT04750785 -
A Study to Assess Choroideremia (CHM) Health Outcomes
|