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Cholecystitis clinical trials

View clinical trials related to Cholecystitis.

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NCT ID: NCT04213092 Completed - Clinical trials for Choledocholithiasis With Cholecystitis With Obstruction

Single Setting ERCP and Laparoscopic Cholecystectomy is a Safe Procedure in Patients With Cholecysto-Choledocholithiasis

Start date: November 2012
Phase:
Study type: Observational

The ideal management of cholecysto-choledocholithiasis is an open cholecystectomy (OC) with the common bile duct (CBD) exploration worldwide. The single setting 2-stage approach- endoscopic retrograde cholangiopancreatography (ERCP), endoscopic sphincterotomy (EST), and CBD clearance followed by laparoscopic cholecystectomy (LC) offers an advantage, mainly by reducing the hospital stay, the cost, and the morbidity. Investigators did a prospective study in patients admitted for the management of the cholecysto-choledocholithiasis in the Department of Surgery at the Lumbini Medical College and Teaching Hospital from November 2012- October 2015. They underwent 2-stage ERCP+LC in a single setting and investigators compared them with 2-stage OC+CBD exploration in a single setting approach. The patients with the open procedure were the investigator's control groups. All the included cases in the study were elective.

NCT ID: NCT04156711 Completed - Clinical trials for Endothelial Dysfunction

Remote Ischemic Preconditioning in Patients Undergoing Acute Minor Abdominal Surgery

PUMAS
Start date: September 4, 2019
Phase: N/A
Study type: Interventional

This study examines if remote ischemic preconditioning in patients undergoing minor acute abdominal surgery (laparoscopic cholecystitis due to acute cholecystitis) is associated with a modulation of endothelial dysfunction. half of the patients will receive remote ischemic preconditioning prior to surgery, the other half will serve as controls.

NCT ID: NCT04146090 Completed - Quality of Life Clinical Trials

Low-pressure vs Standard-pressure in Laparoscopic Cholecystectomy

Start date: October 23, 2019
Phase: N/A
Study type: Interventional

Background. Many studies have demonstrated reduced postoperative pain in patients undergoing lower pneumoperitoneum pressure level during laparoscopic cholecystectomy. However, most of them has shown a high risk of bias and low or very low quality of evidence. Considering the need to evaluate, not only the postoperative pain, but the effect of anesthesia and surgery on patient recovery and satisfaction, we have designed a prospective, randomised and double-blinded study to evaluate the quality of recovery, using the Quality of Recovery Questionnaire (QoR-40), in patients undergoing LC under low-pressure or standard pressure pneumoperitoneum. Methods. Eighty patients aged 18 to 65 years of age will be randomised into 2 groups: LP (low-pressure - 10mmHg) or S (standard - 14 mmHg) enrolled in the study. Anesthesia will be induced with remifentanil, propofol and rocuronium and the maintenance will be achieved with sevoflurane and remifentanil Anesthesiologists and surgeons will not have access to insufflation pressure display. The primary outcome will be assessed using the Quality of Recovery Questionnaire (QoR-40) which is a 40-item quality of recovery scoring system. In addition, the intraoperative rocuronium consumption, time to eye opening (time from the discontinuation of anesthetics to eye opening), post-operative nausea and vomiting, pain score, analgesic use, and length of PACU stay (time to Aldrete score ≥ 9) will be recorded.

NCT ID: NCT04127149 Completed - Pneumonia Clinical Trials

Evaluation of Ultra-portable Ultrasound in General Practice

EPEMedG
Start date: December 3, 2019
Phase: N/A
Study type: Interventional

This is an interventional multi-centre study comparing two groups of general practitioners with or without an ultrasound scanner over a period of 6 months. The evaluation focuses on the management of patients for 8 pathologies: - Pneumonia - Pleural effusion - Renal colic - Hepatic colic or cholecystitis - Subcutaneous abscess or cyst - Fracture of long bones - Intra-uterine pregnancy or extra-uterine pregnancy or miscarriage - Phlebitis The principal hypothesis is that there are fewer complementary exams in the group of doctors using ultrasound scanners. The secondary hypotheses are: - There is better patient orientation (emergency care, specialist consultation, return home) in the group of doctors using the ultrasound scanners. - The global cost of the care is lower in the group of doctors using the ultrasound. - Using ultrasound during the consultation decreases the anxiety of the patient. - Using ultrasound increases the duration of the consultation. - There is no difference between the predicted and the real orientation of the patients.

NCT ID: NCT04122261 Completed - Cholecystitis Clinical Trials

A Clinical Study of Chinese Domestic Surgical Robot

Start date: October 13, 2019
Phase: N/A
Study type: Interventional

This is a prospective, multi-center, randomized, single-blind, parallel-controlled clinical trial to evaluate the safety and efficacy of the Chinese domestic endoscopic instrument control system in clinical treatment.

NCT ID: NCT04059601 Completed - Acute Cholecystitis Clinical Trials

Magnetic Resonance Cholangiography and Intraoperative Cholangiography in Acute Cholecystitis

Start date: January 1, 2019
Phase:
Study type: Observational

The treatment of choice for acute cholecystitis is cholecystectomy performed as soon as possible after onset of symptoms. Up to 9-22% of patients undergoing cholecystectomy due to cholecystitis have common bile duct stones. Magnetic resonance cholangiopancreatography (MRCP) can aid in technical planning of the operation. Intraoperative cholangiography (IOC) is another method to assess anatomy and stones during operation. There is a lack of quality studies comparing findings of MRCP and IOC and effect on hospital admission. The aim of this study is to systematically assess the quality of MRCP and IOC in acute cholecystitis, and observe the effect of routine MRCP on surgery outcomes, length of hospital stay, hospital admission costs, and evaluate whether routine IOC could be replaced by MRCP.

NCT ID: NCT04033211 Completed - Appendicitis Clinical Trials

NOVOsyn® for Trocar Incision After Laparoscopic Appendectomy and Cholecystectomy

NOVOTILAC
Start date: February 13, 2020
Phase:
Study type: Observational

The aim of this study is to evaluate if the application of a Chlorhexidine coated suture (Novosyn® CHD) will reduce the colonization of bacteria in comparison to an uncoated suture (Novosyn®) used for the closure of trocar wounds in laparoscopic surgery (appendectomy and cholecystectomy).

NCT ID: NCT03999645 Completed - Acute Cholecystitis Clinical Trials

Is it Safe to do Laparoscopic Cholecystectomy for Acute Cholecystitis up to Seven Days?

RCT
Start date: September 1, 2017
Phase: N/A
Study type: Interventional

Objectives: To compare the safety of early (≤72h) versus late (>72h-7days) laparoscopic cholecystectomy (LC) from symptom onset for acute cholecystitis (AC). Background: As LC within 72h of symptom onset was considered the optimum time, sometimes there was a delay in diagnosis and management. So, we raised the question of safety and feasibility of performing LC to patients with AC who failed to have LC within 72h of acute attack. Patients and Methods: This was a prospective, randomized, double-blind, clinical trial; carried out on 120 patients presented with AC between September 2017 and April 2019. Patients were randomly allocated into two equal groups assigned to LC; group E: within 72h of symptom onset, and group L: after 72h up to seven days from symptom onset.

NCT ID: NCT03853408 Completed - Acute Cholecystitis Clinical Trials

Short Term Outcomes of Acute Cholecystitis Managed at a University Hospital

Start date: July 26, 2017
Phase:
Study type: Observational

The aim of this retrospective study was to assess the different outcomes of early (performed on the patient's first admission for acute cholecystitis) and delayed cholecystectomy (done on a second admission) at King Abdulaziz University Hospital in Jeddah, Saudi Arabia.

NCT ID: NCT03781687 Completed - Postoperative Pain Clinical Trials

Bilateral vs. Unilateral Erector Spinae Plane Block

Start date: January 2, 2019
Phase: N/A
Study type: Interventional

The importance of multimodal analgesia for postoperative pain management is well known and regional anesthesia techniques are commonly prefferred to provide better analgesia. Erector spinae plane block (ESB) is a new defined and effective regional anesthesia technique. But two injections can be unconfortable for some patients. With this study, we aimed to compare the analgesia effect of bilateral and unilateral ESP block for laparoscopic cholecystectomy.