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Cholangitis clinical trials

View clinical trials related to Cholangitis.

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NCT ID: NCT06365424 Recruiting - Clinical trials for Primary Biliary Cholangitis

Fenofibrate in Patients With Primary Biliary Cholangitis (PBC)

Start date: April 8, 2017
Phase: Phase 2/Phase 3
Study type: Interventional

An Open Label Long-Term Study to Evaluate the Safety and Effectiveness of Fenofibrate in Subjects with Primary Biliary Cholangitis (PBC)

NCT ID: NCT06351696 Recruiting - Ulcerative Colitis Clinical Trials

The Effects of Bromelain Supplement in Patients With Ulcerative Colitis

Start date: April 20, 2024
Phase: N/A
Study type: Interventional

In this study, patients with active mild to moderate UC with or without PSC will be randomized to receive either bromlein or placebo along with low FODMAP diet for 8 weeks. IBDQ, SCCAIQ, CRP, TAC, TNF-a will be measured before and after the intervention.

NCT ID: NCT06349954 Recruiting - Clinical trials for Choledocholithiasis With Acute Cholangitis

Effectiveness and Safety of Single-session Endoscopic Stone Extraction

Start date: April 15, 2024
Phase: N/A
Study type: Interventional

This is a prospective study, including approximately 64 patients with acute cholangitis accompanied with choledocholithiasis at Beijing Friendship Hospital. All patients will be randomly allocate into single-session or two-session endoscopic stone extraction. The investigators assessed the outcomes of single-session and two-session endoscopic stone extraction.

NCT ID: NCT06327126 Recruiting - Clinical trials for Choledocholithiasis With Acute Cholangitis

Efficacy and Safety of Single-session Endoscopic Stone Extraction

Start date: January 1, 2024
Phase:
Study type: Observational

This is a retrospective study, including approximately 600 patients with acute cholangitis accompanied with choledocholithiasis, who treated with single-session or two-session endoscopic stone extraction at Beijing friendship hospital. The investigators assessed the outcomes of single-stage and two-stage endoscopic stone extraction.

NCT ID: NCT06297993 Recruiting - PSC Clinical Trials

Adult Patients With Primary Sclerosing Cholangitis

WIND-PSC
Start date: May 6, 2024
Phase:
Study type: Observational

Develop an appropriate real-world data comparator cohort to support the design, execution, and serve as an external control for interventional clinical trials in PSC.

NCT ID: NCT06286709 Recruiting - Clinical trials for Inflammatory Bowel Diseases

FAecal Microbiota Transplantation in primaRy sclerosinG chOlangitis

FARGO
Start date: March 27, 2024
Phase: Phase 2
Study type: Interventional

FARGO is a randomised, phase IIa, multi-centre, placebo-controlled trial to compare Faecal Microbiota Transplant (FMT) with placebo in patients with primary sclerosing cholangitis (PSC) and concomitant inflammatory bowel disease.

NCT ID: NCT06247735 Recruiting - Clinical trials for Primary Biliary Cholangitis

Study to Evaluate the Efficacy and Safety of K-808 (Pemafibrate) in Participants With Primary Biliary Cholangitis (PBC) With Inadequate Response to Ursodeoxycholic Acid (UDCA) and/or Obeticholic Acid (OCA) Treatment.

Start date: January 26, 2024
Phase: Phase 2
Study type: Interventional

Study to investigate the efficacy and safety of two doses of K-808 (pemafribate) in subjects with PBC.

NCT ID: NCT06197984 Recruiting - Choledocholithiasis Clinical Trials

Antimicrobial Resistance in Acute Cholangitis

ARISE
Start date: January 8, 2024
Phase:
Study type: Observational [Patient Registry]

This study prospectively explores antimicrobial resistance in patients with acute cholangitis undergoing ERCP procedures. By analyzing patient profiles, microbial cultures, and treatment outcomes, the current study seeks to identify specific patterns of resistance, assess the effectiveness of current antimicrobial therapies, and explore potential strategies to optimize treatment regimens.

NCT ID: NCT06197308 Recruiting - Clinical trials for Primary Sclerosing Cholangitis

Evaluation of an Oral Microbiota-based Therapeutic as a Treatment Option for PSC

Start date: March 1, 2024
Phase: Early Phase 1
Study type: Interventional

This pilot clinical trial will evaluate the initial safety and feasibility of microbiota transplant therapy (MTT) inpatients with primary sclerosing cholangitis (PSC). This trial will inform development of future trials in treatment of PSC.

NCT ID: NCT06174402 Recruiting - Clinical trials for Primary Biliary Cholangitis

Fenofibrate in Combination With Ursodeoxycholic Acid in Primary Biliary Cholangitis

Start date: August 21, 2023
Phase: Phase 2/Phase 3
Study type: Interventional

The main objectives of the study were to assess the effects of fenofibrate on serum alkaline phosphatase, as a composite endpoint and on safety in participants with primary biliary cholangitis (PBC)