Children Clinical Trial
Official title:
New Tools for Predicting Capillary Leak Shock During Dengue Fever
Evaluate the prognostic value of different methods (Osmometry / clinical-biological score) compared to the occurrence of capillary leak shock during dengue fever.
On the South American continent, dengue fever progressively progresses to hyperendemia with co-circulation of different serotypes. Among the complications of dengue fever, a frequent complication is the shock linked to capillary leakage which often occurs at the time of defervescence between the 3rd or 5th day of evolution of the fever. Before that, it is difficult to identify patients who are at risk for severe forms. Patients are therefore seen regularly to monitor for the development of serious forms, which causes saturation of the health system. Despite everything, with each epidemic, the investigators observe deaths of previously healthy people, which always constitutes an important trauma for the population and for the carers. Improving the understanding of the pathophysiology of capillary leakage and the tools to predict it would be significant advances in this common tropical pathology. Thus a retrospective study of longitudinal data during the dengue 2 epidemic of 2013 made it possible to generate precise hypotheses as to the pathophysiology of the shock linked to capillary leakage. Hypoprotidemia and hyponatremia having a strong statistical association with the subsequent occurrence of shock, the hypothesis is of a progressive disturbance of the plasma osmolarity resulting in water leaks towards the interstitial sector. These preliminary data also made it possible to develop a predictive score which must now be validated over time. Research involving the human person, monocentric, prospective, validation Interventional research protocol involving the human person category 2 at risk and minimal constraints ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT03563196 -
Diagnosis Of Pulmonary Complications After Cardiac Surgery In Children
|
||
| Completed |
NCT02553486 -
Internationally Adopted Children Quality of Life
|
N/A | |
| Completed |
NCT02903134 -
Early Risk of Asthma in Children Exposed to In-utero Maternal Obesity
|
||
| Completed |
NCT02918890 -
Intensive Unimanual (CIMT) and Bimanual Training (HABIT) in Children With Hemiplegia
|
N/A | |
| Active, not recruiting |
NCT01874847 -
PLAY GAME: Post-concussion Syndrome in Youth - Assessing the GABAergic Effects of Melatonin
|
Phase 2/Phase 3 | |
| Enrolling by invitation |
NCT01971827 -
Effectiveness of a Physical Activity Intervention to Prevent Obesity and Improve Academic Performance
|
N/A | |
| Enrolling by invitation |
NCT01971840 -
Effectiveness of a Physical Activity Intervention on Preventing Obesity During the Adiposity Rebound Period.
|
N/A | |
| Completed |
NCT01738308 -
The Effects of Healing Touch on Post Operative Pediatric Patients
|
N/A | |
| Completed |
NCT01864811 -
Effect of Baby-CIMT in Infants Younger Than 12 Months
|
N/A | |
| Completed |
NCT01943760 -
Tamadol Wound Infiltration in Children Under Inguinal Hernioplasty
|
Phase 4 | |
| Completed |
NCT01693926 -
Effect of Physical Activity an Stress in Children
|
N/A | |
| Completed |
NCT01323010 -
Efficacy and Safety of Increasing Doses of Inhaled Albuterol in Children With Acute Wheezing Episodes
|
N/A | |
| Completed |
NCT01277224 -
Effectiveness of a Physical Activity Intervention on the Obesity of Schoolchildren
|
N/A | |
| Active, not recruiting |
NCT00989547 -
Cord Blood Infusion for Type 1 Diabetes Mellitus (T1DM)
|
Phase 1 | |
| Completed |
NCT04051723 -
Pre-emptive Scalp Infiltration With Dexamethasone Plus Ropivacaine for Post-Craniotomy Pain in Children
|
Phase 4 | |
| Completed |
NCT03236363 -
Effectiveness of MOVI Interventions on Adiposity, Cognition and Motor Competence: MOVI-da10!
|
N/A | |
| Completed |
NCT03236337 -
Effectiveness of MOVI Interventions on Adiposity, Cognition and Subclinical Atherosclerosis: MOVI-daFit!
|
N/A | |
| Not yet recruiting |
NCT03427697 -
Effect of VR and Accommdation Relax on Controlling Myopia in Children
|
N/A | |
| Completed |
NCT05603507 -
Inspiratory Muscle Training in Children With Chest Burn
|
N/A | |
| Not yet recruiting |
NCT06267339 -
Effects of Transcranial Random Noise Stimulation on Motor Learning in Typically Developing Adolescents
|
Early Phase 1 |