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Chemotherapy clinical trials

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NCT ID: NCT05251727 Recruiting - Clinical trials for Chemotherapy-induced Peripheral Neuropathy

Assess Safety and Tolerability of ART-123 + FOLFOX + Bevacizumab in Metastatic Colorectal Cancer Patients

Start date: March 24, 2022
Phase: Phase 1
Study type: Interventional

To evaluate the safety and tolerability of ART-123 in patients with metastatic colorectal cancer who receive oxaliplatin-containing chemotherapy and bevacizumab

NCT ID: NCT05244837 Recruiting - Safety Clinical Trials

Predictive Biomarker for Efficacy and Safety of Combination of Chemotherapy and Tislelizumab in NSCLC

Start date: December 22, 2020
Phase: Phase 2
Study type: Interventional

To explore the related biomarkers for safety and efficacy of the combination of chemotherapy and tislelizumab in non-small cell lung cancer

NCT ID: NCT05239663 Recruiting - Breast Cancer Clinical Trials

GM1 Prophylaxis for Post-chemotherapy Cognitive Impairment in Patients With Early Operable Breast Cancer

Start date: February 8, 2022
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the prophylactic effects of Ganglioside-Monosialic Acid in post-chemotherapy cognitive impairment in patients with early operable breast cancer.

NCT ID: NCT05236582 Recruiting - Clinical trials for Chemotherapy-induced Thrombocytopenia

Herombopag for Chemotherapy-induced Thrombocytopenia

Start date: March 14, 2022
Phase: Phase 2
Study type: Interventional

To evaluate the efficacy and safety of Herombopag to treat chemotherapy-induced thrombocytopenia in Solid Tumors

NCT ID: NCT05218226 Recruiting - Clinical trials for Chemotherapy-induced Thrombocytopenia

Avatrombopag for Chemotherapy-induced Thrombocytopenia

Start date: February 10, 2022
Phase: Phase 2
Study type: Interventional

To evaluate the efficacy and safety of Avatrombopag to treat chemotherapy-induced thrombocytopenia in solid tumors

NCT ID: NCT05216237 Recruiting - Gastric Cancer Clinical Trials

A Study to Evaluate the Efficacy and Safety of Sintilimab Plus Apatinib and Chemotherapy in Patients With HER-2 Negative Microsatellite Stability (MSS) Advanced or Metastatic Gastric (GC) or Gastroesophageal Junction (GEJ) Cancer

Start date: February 15, 2022
Phase: Phase 2
Study type: Interventional

To evaluate the efficacy and safety of Sintilimab combined with apatinib and chemotherapy as First-line or second-line Therapy in Treatment of HER-2 negative MSS Advanced or Metastatic GC or GEJ Cancer. At the same time, the correlation between tissue programmed death ligand-1(PD-L1) expression and blood circulating tumor cell(CTC) counts and the efficacy of immune combination therapy was also explored.

NCT ID: NCT05199818 Recruiting - Clinical trials for Chemotherapy-induced Nausea and Vomiting

Buccal Film vs IV Palonosetron for Prevention of CINV in Cancer Patients Receiving MEC

Start date: March 1, 2022
Phase: Phase 3
Study type: Interventional

The phase 3 study is to compare the efficacy and safety of palonosetron, a long-acting 5-HT3 receptor antagonist, by buccal film delivery compared to IV injection for the prevention of chemotherapy-induced nausea and vomiting. Subjects receive a single dose of palonosetron prior to moderately emetogenic chemotherapy.

NCT ID: NCT05143554 Recruiting - Clinical trials for Chemotherapy-induced Nausea and Vomiting

Auricular Neurostimulation for Chemotherapy Induced Nausea and Vomiting

Start date: April 29, 2021
Phase: N/A
Study type: Interventional

This study evaluates the efficacy of auricular percutaneous electrical nerve field stimulator in children, adolescents and young adults with chemotherapy induced nausea and vomiting.

NCT ID: NCT05125055 Recruiting - Chemotherapy Clinical Trials

Neoadjuvant Anti-PD-1 and TP Versus TPF on Pathological Response in OSCC

Start date: October 1, 2021
Phase: Phase 2/Phase 3
Study type: Interventional

To compare the pathological efficacy of neoadjuvant Toripalimab and Albumin paclitaxel /Cisplatin (TTP) with Docetaxel/ Cisplatin/ 5-flurouracil (TPF) for patients with locally advanced resectable oral squamous cell carcinoma (OSCC), and to determine the safety of neoadjuvant TTP. In order to explore a better protocol of neoadjuvant therapy to improve the efficacy in patients with locally advanced OSCC.

NCT ID: NCT05121558 Recruiting - Clinical trials for Chemotherapy-Induced Peripheral Neuropathy

The Effect of Yoga on Nerve Pain Caused by Chemotherapy (Chemotherapy-Induced Peripheral Neuropathy)

Start date: October 29, 2021
Phase: Phase 3
Study type: Interventional

The purpose of this study is to test whether yoga can reduce nerve pain caused by cancer treatment (chemotherapy-induced peripheral neuropathy, or CIPN). Participants will take one of three approaches: - Yoga classes - Educational sessions on the causes and impacts of CIPN, how yoga may help with CIPN, and how different therapies may help with CIPN - Usual care with standard-of-care medications for CIPN The researchers will compare how these different approaches affect participants' balance, their risk of falls, and their quality of life. This study will also measure how much yoga can help the reduced sense of touch caused by CIPN. The functional assessments TUG and CTS can be safely completed either virtually and in-person and will be mandatory for all patients. The functional assessment FRT and QST assessments that can only be completed in-person are optional at these time points.