Celiac Disease Clinical Trial
Official title:
Nutritional Intake and Bone Health Among Adults With Undiagnosed, Untreated Celiac Disease
Celiac disease leads to malnutrition and secondary conditions including osteoporosis. The dietary habits of adults with untreated, undiagnosed celiac disease has not yet been observed, but presents a critical piece in understanding the effects of the disease on bone health. Objective was to evaluate differences in nutritional intake of calcium, vitamin D, and phosphorus; serologic indices of these nutrients; and bone health among adults with and without celiac disease. Cross-sectional data from What We Eat in America (WWEIA) and the National Health and Nutrition Examination Survey (NHANES) 2009-14 was analyzed.
Celiac disease leads to malnutrition and secondary conditions including osteoporosis. The
dietary habits of adults with untreated, undiagnosed celiac disease has not yet been
observed, but presents a critical piece in understanding the effects of the disease on bone
health. Objective was to evaluate differences in nutritional intake of calcium, vitamin D,
and phosphorus; serologic indices of these nutrients; and bone health among adults with and
without celiac disease.
Cross-sectional data from What We Eat in America (WWEIA) and the National Health and
Nutrition Examination Survey (NHANES) 2009-14 was analyzed, including self-reported dietary
and supplement intake from one day of 24-hour recalls, serologic indicators, and dual x-ray
absorptiometry (DXA) scans were analyzed in adults (n=49) testing positive for celiac disease
to the tissue transglutaminase endomysial antibody assay (tTG-EMA). Statistical analysis
included multiple linear regression modelling controlled for age, sex, race/ethnicity, energy
intake, and poverty income ratio.
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