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Assessment of Duodenal Epithelial Integrity in Celiac Disease With Mucosal Impedance

Celiac Disease Clinical Trial

Official title:
Assessment of Duodenal Epithelial Integrity in Celiac Disease With Mucosal Impedance

Clinical Trial Summary

Increased intestinal permeability can represent compromise of the epithelium's integrity and is thought to be the primary mechanism in patients who develop Celiac Disease (CeD) and non-celiac gluten sensitivity when gluten peptides cross the barrier and trigger an immune response. In this study, the investigators propose to use a novel, minimally invasive technology to detect mucosal damage (i.e. barrier dysfunction) in the duodenal epithelium. The primary aim of this study is to identify if there is a difference in duodenal mucosal impedance between CeD and control patients.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03152279
Study type Observational
Source Vanderbilt University Medical Center
Contact
Status Completed
Phase
Start date December 2016
Completion date November 14, 2018
View Details
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