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Cataract clinical trials

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NCT ID: NCT00827073 Completed - Cataracts Clinical Trials

Comparison of Tetracaine 0.5% and Lidocaine 2% Jelly for Topical Phacoemulsification Cataract Surgery

Start date: November 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if there is a difference on the penetration of betadine 5% when using lidocaine 2% jelly versus topical tetracaine 0.5% in topical cataract surgery. This will be assessed comparing bacterial colony count and species by taking swabs from the eye surface before and after the topical anesthesia has been administered.

NCT ID: NCT00825864 Completed - Cataract Clinical Trials

Diclofenac vs Dexamethasone in Combined Surgery

Start date: January 2004
Phase: N/A
Study type: Interventional

To study the effect of Diclofenac drops or Dexamethasone drops on combined surgery of trabeculectomy and cataract surgery.

NCT ID: NCT00825513 Completed - Cataract Clinical Trials

Safety and Effectiveness of the Akreos Toric Intraocular Lens.

Start date: February 2009
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the safety and effectiveness of the Akreos Toric IOL following cataract surgery.

NCT ID: NCT00821223 Completed - Quality of Life Clinical Trials

Outcome Following Phacoemulsification Versus Small Incision Cataract Surgery (SICS)

Start date: February 2009
Phase: N/A
Study type: Interventional

Hypothesis : Phacoemulsification is superior to SICS with regards to: - Immediate unaided high and low contrast visual performance - Its impact on quality of life.

NCT ID: NCT00820014 Completed - Cataract Clinical Trials

Ocular Biodistribution Study for Topically Applied ESBA105

Start date: January 2009
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to determine whether ESBA105, a single-chain (scFv) antibody against TNF-alpha, efficiently penetrates into the anterior chamber and the vitreous body upon topical administration to the eye.

NCT ID: NCT00818116 Completed - Cataracts Clinical Trials

Visual Function Evaluation of Bilateral AcrySof ReSTOR Aspheric IOL

Start date: December 2008
Phase: Phase 4
Study type: Interventional

The objective of this study is to evaluate postoperative visual function in patients implanted bilaterally with the ReSTOR Aspheric Intraocular Lens (IOL).

NCT ID: NCT00806832 Completed - Blood Pressure Clinical Trials

The Effects of Medical Clowning on Blood Pressure and Pulse Rate of Patients Undergoing Cataract Surgery Under Local Anesthesia

Start date: December 2008
Phase: N/A
Study type: Observational

Cataract surgery is the most prevalent surgical procedure. Since most candidates are elderly patients, hypertension is common among these patients. Preoperative anxiety and tension may cause elevation of patient's heart rate and blood pressure and thus expose them to serious potential complications such as stroke and myocardial infarction. Medical clowns are known to reduce preoperative anxiety of both children and their parents. It is possible therefore that medical clown may have such a beneficial effect also on patients scheduled for cataract surgery under local anesthesia.

NCT ID: NCT00801359 Completed - Cataract Clinical Trials

BSSPlus Versus Lactated Ringer's for Phacoemulsification

Start date: January 2008
Phase: Phase 2
Study type: Interventional

Two intraocular irrigating solutions (BSSPlus versus Lactated Ringer's) are compared in this prospective, randomized, masked trial to investigate for differences in preservation of corneal integrity after phacoemulsification cataract surgery.

NCT ID: NCT00786565 Completed - Cataract Clinical Trials

Clinical Evaluation of a New Aspheric Intraocular Lens.

Start date: January 2004
Phase: Phase 4
Study type: Interventional

This study evaluates the visual performance and occurrence of posterior capsular opacification after implantation of a new aspherical intraocular lens compared with a control spherical lens of otherwise identical design.

NCT ID: NCT00786370 Completed - Cataract Clinical Trials

Dexmedetomidine vs. Propofol for Cataract Surgery

Start date: April 2008
Phase: Phase 4
Study type: Interventional

The use of dexmedetomidine in cataract surgery is still limited and to date only one study has examined anesthetic technique in this patient population. This pilot study will therefore compare the use of dexmedetomidine and propofol in subjects undergoing cataract surgery. The primary endpoint will be based on simple cardiorespiratory measures often associated with complications from sedation as well as assessment of the achieved sedation by the attending anesthesiologist and surgeon.