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Cataract clinical trials

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NCT ID: NCT00969371 Completed - Cataract Clinical Trials

Lenstec Tetraflex Accommodating Posterior Chamber Intraocular Lens (IOL) Clinical Investigation

Start date: September 2005
Phase: N/A
Study type: Interventional

The purpose of the following clinical protocol is to evaluate the safety and effectiveness of the Lenstec Tetraflex Accommodating Posterior Chamber Intraocular Lens (IOL) for the protocol inclusion/exclusion criteria.

NCT ID: NCT00967473 Completed - Clinical trials for Adult Patients With Bilateral Cataracts.

ACRYSOF® Toric NATURAL T9 Intraocular Lens (IOL)

Start date: August 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to describe rates of spatial distortions related to intraocular lens (IOL) misalignment for ACRYSOF® Single-Piece Toric NATURAL IOL Model SN60T9 when implanted bilaterally into the capsular bag following phacoemulsification in adult patients with bilateral cataract and regular corneal astigmatism. Subjects were implanted with the Model SN60T9 in the first operative (study) eye and either Model SN60T9 or Model SN60T8 in the second operative eye.

NCT ID: NCT00963742 Completed - Cataract Clinical Trials

Lenstec Softec HD Posterior Chamber Intraocular Lens Clinical Investigational Protocol

Start date: December 2006
Phase: N/A
Study type: Interventional

The objectives of this multi-center clinical investigation are to determine the safety and effectiveness of the Lenstec Softec HD Posterior Chamber intraocular lens (IOL) following one year of post-operative assessment.

NCT ID: NCT00963560 Completed - Cataract Clinical Trials

Presbyopia-Correcting Intraocular Lenses (IOLs)

Start date: August 2009
Phase: Phase 4
Study type: Interventional

The purpose of this study is to prospectively evaluate postoperative visual and refractive parameters in a series of subjects bilaterally implanted with Presbyopia-Correcting Intraocular Lenses (IOLs).

NCT ID: NCT00959322 Completed - Cataract Clinical Trials

A Prospective Single Center Clinical Study for Capsulotomy Using the LenSx 550 Laser

Start date: August 2008
Phase: N/A
Study type: Interventional

The LenSx 550 laser system is a femtosecond laser intended for use in performing anterior capsulotomy during cataract surgery. The anterior capsulotomy creates a circular opening in the anterior surface of the capsular bag that contains the cataractous crystalline lens. The objective of this study is to evaluate the ability of the LenSx 550 laser to successfully perform anterior capsulotomy during cataract surgery.

NCT ID: NCT00934622 Completed - Cataract Clinical Trials

Visual Function After Implantation of Bilateral AcrySoft ReSTOR Aspheric IOL

Start date: November 2007
Phase: Phase 4
Study type: Interventional

This study will involve up to 20 bilateral patients per surgeon. Patients will be assessed pre-operatively, and at subsequent visits (following the implantation of the intraocular lens in the second eye) at 1 week, 1 month, 3 months and 6 months post-operatively.

NCT ID: NCT00925600 Completed - Prostate Cancer Clinical Trials

A Study to Evaluate New or Worsening Lens Opacifications in Subjects With Non-metastatic Prostate Cancer Receiving Denosumab for Bone Loss Due to Androgen-Deprivation Therapy

Start date: November 2009
Phase: Phase 3
Study type: Interventional

This is a phase 3, randomized, double-blind, placebo-controlled study to evaluate new or worsening lens opacifications in subjects with non-metastatic prostate cancer receiving denosumab for bone loss due to androgen deprivation therapy.

NCT ID: NCT00924729 Completed - Cataract Extraction Clinical Trials

Study of Ocular Penetration of Topically Administered Fluoroquinolones

Start date: September 2009
Phase: Phase 4
Study type: Interventional

This study is being conducted to evaluate the intraocular penetration of Moxifloxacin 0.5% ophthalmic solution (Vigamox) and Besifloxacin 0.6% ophthalmic suspension (Besivance) after pre-operative topical administration in subjects undergoing cataract surgery.

NCT ID: NCT00921297 Completed - Alzheimer's Disease Clinical Trials

Cataract Removal and Alzheimer's Disease

Start date: June 2009
Phase: N/A
Study type: Interventional

Two very common aging-related diseases in older adults are Alzheimer's disease (AD) and cataracts. In elderly adults, these two diseases frequently occur in the same person. Although a cure for AD is currently unavailable, cataracts can be effectively treated with surgery in most people. The removal of cataracts has documented benefits for visual performance and for reducing accidents and falls. However, it has been the experience of the ophthalmologists, and others in the field, that patients, caregivers, and primary care doctors are reluctant to proceed with cataract surgery once an individual is given the diagnosis of AD. It is thought that cataract surgery will not improve the AD patient's quality of life, vision, and cognition. The investigators have designed this study to determine whether or not this is true.

NCT ID: NCT00905450 Completed - Inflammation Clinical Trials

Evaluation of BOL-303242-X Versus Vehicle for the Treatment of Inflammation Following Cataract Surgery

Start date: June 2009
Phase: Phase 2
Study type: Interventional

This clinical study is being conducted to identify the most effective drug concentration and dose frequency of BOL-303242-X (Mapracorat) ophthalmic suspension, for the treatment of inflammation following cataract surgery.