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Cataract clinical trials

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NCT ID: NCT00446277 Suspended - Diabetes Mellitus Clinical Trials

Corneal Endothelial Cell Loss in Diabetes Type II During Cataract Surgery

Start date: January 2007
Phase: Phase 4
Study type: Observational

The aim of the present study is to evaluate changes in the morphology and function of the corneal endothelium before and after cataract surgery in patients with diabetes type II. Also to explain if determination of HgbA1c in diabetics is a predictor for the changes in morphology and function.

NCT ID: NCT00434707 Not yet recruiting - Cataract Clinical Trials

Outcome of Small Pupil Phacotrabeculectomy in Persons With Glaucoma and Cataract

Start date: March 2007
Phase: N/A
Study type: Observational

Small pupils are not uncommon in situations requiring surgical intervention for glaucoma and cataract. Inadequate binocular view during combined trabeculaectomy and glaucoma surgery needs to be overcome by additional iris manupulations to dilate the pupils which increase the liklihood of inflammation, inraocular pressure rise after surgery and enhnced liklihood of failure of glaucoma surgery. The proposed trial is an observational study to analyse post operative outcome of eyes undrgoing trabeculectomy and phacoemulsification with intraocular lens implantation with small pupils in persons with glaucoma coexisting with cataract.

NCT ID: NCT00432874 Completed - Cataract Clinical Trials

Prospective Evaluation of Safety and Efficacy of Two Forms of Corneal Stromal Hydration

Start date: February 2007
Phase: N/A
Study type: Interventional

The study objective is to compare traditional and Wong methods of wound hydration for wound sealing following cataract surgery.

NCT ID: NCT00431028 Terminated - Inflammation Clinical Trials

Sub-Tenon's Injection of Triamcinolone and Ciprofloxacin in a Controlled-Release System for Cataract Surgery

Start date: September 2005
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to compare one intraoperative sub-Tenon's capsule injection of triamcinolone and ciprofloxacin in a biodegradable controlled-release system with conventional prednisolone and ciprofloxacin eye drops to treat ocular inflammation and for infection prophylaxis after cataract surgery.

NCT ID: NCT00428363 Completed - Cataract Clinical Trials

Effect of Optic Edge Design in a Silicone Intraocular Lens on Posterior Capsule Opacification

Start date: June 2001
Phase: Phase 4
Study type: Interventional

Purpose: To compare the posterior capsule opacification (PCO) inhibiting effect of the sharp posterior optic edge design of the Clariflex silicone intraocular lens (IOL) with that of the double-round edge design of the SI40 (Phacoflex) silicone IOL over a period of 3 years. Setting: Department of Ophthalmology, Medical University of Vienna, Vienna, Austria. Methods: Fifty-two patients with bilateral age-related cataract (104 eyes) were included in this randomized, prospective, bilateral, patient- and examiner-masked clinical trial with intra-individual comparison. Each study patient had cataract surgery in both eyes and received an SI40 IOL (anterior and posterior round optic edges) in one eye and a Clariflex IOL with OptiEdge (round anterior and sharp posterior optic edge) in the other eye. Follow-up examinations were at one week, one month, six months, one, two, and three years. Digital retroillumination images were taken of each eye. The amount of PCO was assessed subjectively at the slit-lamp and objectively using automated image analysis software (AQUA) one, two, and three years after surgery.

NCT ID: NCT00425464 Terminated - Cataract Clinical Trials

A Prospective Multicenter Clinical Study to Evaluate the Safety and Effectiveness of the Synchrony Dual Optic Intraocular Lens in Patients Undergoing Cataract Extraction

Start date: November 2005
Phase: Phase 3
Study type: Interventional

The purpose of the study is to determine if the Synchrony Dual Optic Accommodating Intraocular Lens can be used safely and effectively in post cataract extraction subjects

NCT ID: NCT00407017 Completed - Cataract Surgery Clinical Trials

Therapeutic Variables in Cataract Surgery

Start date: n/a
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare patient outcomes in following cataract surgery in patients randomized to one of two surgical kits.

NCT ID: NCT00406913 Completed - Cataract Surgery Clinical Trials

Prophylaxis Prior to Cataract Surgery Conjunctival Flora and Optimal Ocular Sterilization Technique Prior to Cataract Surgery

Start date: October 2005
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the conjunctival flora prior to cataract or vitrectomy surgery comparing mupirocin ointment applied to the conjunctiva along with standard ocular sterilization vs. standard ocular sterilization alone.

NCT ID: NCT00406263 Completed - Clinical trials for Nuclear Sclerotic Cataract

Comparison of Scheimpflug Photos of the Crystalline Lens in Patients Who Have Undergone Vitrectomy Surgery and Controls

Start date: November 2006
Phase: N/A
Study type: Observational

Progression of nuclear sclerotic cataract after pars plana vitrectomy has been recognized for many years The mechanism for the rapid progression of nuclear sclerotic cataract remains unclear. The objective of this trial is to evaluate and compare the level and progression of cataract advancement in controls versus eyes that have undergone 20-gauge pars plana vitrectomy and 25-gauge pars plana vitrectomy.

NCT ID: NCT00405730 Completed - Cataracts Clinical Trials

Nepafenac 0.1% Eye Drops, Suspension Compared to Ketorolac Trometamol 0.5% Eye Drops, Solution and Placebo

Start date: November 2005
Phase: Phase 3
Study type: Interventional

To evaluate the safety and efficacy of Nepafenac 1 mg/ml Eye Drops, Suspension, compared to Placebo and Ketorolac Trometamol 5 mg/ml Eye Drops, Solution for the prevention and treatment of ocular inflammation and ocular pain after cataract extraction with IOL implantation