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Cataract clinical trials

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NCT ID: NCT00925600 Completed - Prostate Cancer Clinical Trials

A Study to Evaluate New or Worsening Lens Opacifications in Subjects With Non-metastatic Prostate Cancer Receiving Denosumab for Bone Loss Due to Androgen-Deprivation Therapy

Start date: November 2009
Phase: Phase 3
Study type: Interventional

This is a phase 3, randomized, double-blind, placebo-controlled study to evaluate new or worsening lens opacifications in subjects with non-metastatic prostate cancer receiving denosumab for bone loss due to androgen deprivation therapy.

NCT ID: NCT00924729 Completed - Cataract Extraction Clinical Trials

Study of Ocular Penetration of Topically Administered Fluoroquinolones

Start date: September 2009
Phase: Phase 4
Study type: Interventional

This study is being conducted to evaluate the intraocular penetration of Moxifloxacin 0.5% ophthalmic solution (Vigamox) and Besifloxacin 0.6% ophthalmic suspension (Besivance) after pre-operative topical administration in subjects undergoing cataract surgery.

NCT ID: NCT00922571 Terminated - Cataract Clinical Trials

A Study of Cataract Surgery With the Femtosecond Laser

Start date: June 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the feasibility of using the Femtosecond Laser System to perform surgical maneuvers during cataract extraction surgery.

NCT ID: NCT00921297 Completed - Alzheimer's Disease Clinical Trials

Cataract Removal and Alzheimer's Disease

Start date: June 2009
Phase: N/A
Study type: Interventional

Two very common aging-related diseases in older adults are Alzheimer's disease (AD) and cataracts. In elderly adults, these two diseases frequently occur in the same person. Although a cure for AD is currently unavailable, cataracts can be effectively treated with surgery in most people. The removal of cataracts has documented benefits for visual performance and for reducing accidents and falls. However, it has been the experience of the ophthalmologists, and others in the field, that patients, caregivers, and primary care doctors are reluctant to proceed with cataract surgery once an individual is given the diagnosis of AD. It is thought that cataract surgery will not improve the AD patient's quality of life, vision, and cognition. The investigators have designed this study to determine whether or not this is true.

NCT ID: NCT00905450 Completed - Inflammation Clinical Trials

Evaluation of BOL-303242-X Versus Vehicle for the Treatment of Inflammation Following Cataract Surgery

Start date: June 2009
Phase: Phase 2
Study type: Interventional

This clinical study is being conducted to identify the most effective drug concentration and dose frequency of BOL-303242-X (Mapracorat) ophthalmic suspension, for the treatment of inflammation following cataract surgery.

NCT ID: NCT00904904 Completed - Inflammation Clinical Trials

Indomethacin Eyedrops Compared With Ketorolac Eyedrops for Ocular Inflammation Following Cataract Surgery

Start date: April 2008
Phase: Phase 4
Study type: Interventional

This study is being conducted to show that indomethacin is at least as effective as ketorolac for the prevention of ocular inflammation following cataract surgery.

NCT ID: NCT00886249 Withdrawn - Cataract Clinical Trials

Depth of Focus Comparison Between Acrysof IQ and Acrysof Natural IOLs

Start date: March 2009
Phase:
Study type: Observational

The purpose of this study is to evaluate and compare the depth of focus and visual outcomes after implantation of the Acrysof IQ SN60WF aspheric intraocular lens (IOL) and the Acrysof Natural SN60AT spherical IOL.

NCT ID: NCT00876707 Completed - Cataract Clinical Trials

Wavefront Analyzes and Visual Performance of Three Multifocal Intra-ocular Lenses

IOL
Start date: March 2009
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to determine if differences in the design of multifocal intra-ocular lenses would mean different values of higher-order aberrations and different performance in objective parameters such as modulation transfer function.

NCT ID: NCT00876278 Withdrawn - Cataract Clinical Trials

Night Driving Pilot

Start date: June 2009
Phase: Phase 4
Study type: Interventional

Pilot study to evaluate usability of Mesotest II for assessment of night driving capacity of pseudo-phakic patients implanted with aspheric monofocal posterior chamber IOL *AT.Smart 46LC. Target Criterion: Measurement of contrast sensitivity and sensitivity to light under mesopic conditions (Mesotest II, Oculus).

NCT ID: NCT00870103 Completed - Cataract Clinical Trials

Study of Efficacy and Safety of Vigadexa in Treating Inflammation and Infection Post-cataract Surgery

Start date: September 2008
Phase: Phase 4
Study type: Interventional

To demonstrate that the combination formulation of Moxifloxacin/Dexamethasone Eye Drop is effective and safe for the prevention of postoperative inflammation as a consequence of cataract extraction surgery.