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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT00976014
Other study ID # 30519
Secondary ID
Status Completed
Phase
First received
Last updated
Start date December 26, 2006
Est. completion date May 9, 2012

Study information

Verified date December 2021
Source University of Washington
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

This observational study looks at Carotid Stenosis in two groups of subjects using a non-invasive procedure, B-mode ultrasound. One group of subjects has had long-term intensive lipid altering therapy (lowering LDL-C plus raising HDL-C). The second group of patients has been on conventional "standard of care" treatment for carotid stenosis. The study will look at the Carotid Intima-media Thickness (CMIT) in both groups. Hypothesis: CIMT will differ between the two groups, such that the CIMT will be less in the subjects on intensive lipid altering therapy.


Recruitment information / eligibility

Status Completed
Enrollment 76
Est. completion date May 9, 2012
Est. primary completion date May 9, 2012
Accepts healthy volunteers No
Gender Male
Age group N/A and older
Eligibility Inclusion Criteria: - Intensive Lipid-lowering Therapy Group: Subjects currently enrolled in the Familial Atherosclerosis Treatment Observational Study. - Usual Care Group: Subjects who were in the FATS OS Study in the past, but have since quit the study and opted for conventional "standard of treatment". Exclusion Criteria: - No past or present participation in the FATS OS Study.

Study Design


Related Conditions & MeSH terms


Locations

Country Name City State
United States University of Washington Seattle Washington

Sponsors (1)

Lead Sponsor Collaborator
University of Washington

Country where clinical trial is conducted

United States, 

References & Publications (1)

Phan BA, Moore AB, Davis J, Pollan LJ, Neradilek B, Brown BG, Zhao XQ. Prolonged combination lipid therapy is associated with reduced carotid intima-media thickness: a case-control study of the 20-year Familial Atherosclerosis Treatment - Observational St — View Citation

Outcome

Type Measure Description Time frame Safety issue
Primary Carotid Intima-media Thickness Up to 3 years
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