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NCT ID: NCT05505084 Recruiting - Caries Clinical Trials

Alveolar Ridge Preservation Following Tooth Extraction.

Start date: August 15, 2022
Phase:
Study type: Observational [Patient Registry]

Bone resorption after a tooth extraction is a generally accepted knowledge and has been demonstrated by many animal and human studies. Especially during the first three months followed by the tooth extraction, the volume of bone may change significantly without any interference. Thus, doing a ridge preservation procedure following the extraction is a common standard of care method to maintain the socket volume if implant placement is considered as a treatment option in the future. A variety of materials and methods have been used for ridge preservation. However, it's still inconclusive to determine the best material to maintain the ridge dimension, especially for membrane placement that allows for space maintenance to protect the grafting material. Furthermore, there is no evidence to show any treatment rationale is superior to any other ridge preservation method. In general, the membrane serves the function of the barrier and space protector. The periodontal surgeon use membranes to exclude the epithelium growth and to limit the collapse of the soft tissue into the healing alveolar socket. Regarding resorbable and non-resorbable membrane materials, both serve the function of protecting the graft material from the oral cavity. However, there are also many demonstrating that without membranes the extraction socket healed nicely without any interferences. The question to us is: Do we need the membrane to exclude the epithelium or any kind of surgical dressing material is sufficient enough to preserve the volume of the extracted ridge? The object of this study is to compare five popular membranes on the market that present different characteristics of the membranes.

NCT ID: NCT05314842 Not yet recruiting - Caries Clinical Trials

Pulpotomy in Primary Molars Treated With Premixed Bio-ceramic MTA Versus Formocresol

Start date: April 1, 2022
Phase: Phase 3
Study type: Interventional

examine the results of pulpotomy in primary molars using premixed bioceramic MTA versus Formocresol. Clinical and radiographic success rates were used as outcomes.

NCT ID: NCT05311657 Active, not recruiting - Quality of Life Clinical Trials

Oral Health and Severe COPD

Start date: September 21, 2020
Phase:
Study type: Observational

This case-control study aims to investigate the association of severe COPD with oral health.

NCT ID: NCT05301439 Not yet recruiting - Caries Clinical Trials

Use Of Hall Technique In Deciduous Molars Affected By Extensive Caries Lesions

Start date: June 20, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

Despite preventive treatments and the promotion of oral health, dental caries is one of the most prevalent chronic diseases in the population and treatment of caries lesions in deciduous teeth is a fundamental procedure aimed at increasing the resistance of the remaining tooth structure to preserve the permanent dentition. The present study aims to make a clinical evaluation of the Hall Technique compared to direct restorations with universal adhesives and bulk fill resins in large destruction of deciduous teeth. 90 children between 5 and 10 years old, healthy, of both sexes, without distinction of race, enrolled in the clinics of Universidade Metropolitana de Santos-UNIMES will be selected. The in-office treatments will be carried out by a trained researcher, according to the manufacturer's instructions for each material and scientific evidence on the respective topic. Participants will be divided into 03 groups according to the proposed treatments. Group 1 - Universal adhesive restorative procedure + condensable bulk fill resin; Group 2 - Hall Technique with Shofu steel crowns and Group 3 - Steel crown with conventional technique. The evaluated outcomes will be: effectiveness of the technique and longevity of the restorations.

NCT ID: NCT05279781 Recruiting - Caries Clinical Trials

Outcome of Pulpotomy Versus Root Canal Therapy

Start date: April 1, 2019
Phase: N/A
Study type: Interventional

Root canal therapy (RCT) is indicated once the pulp is diagnosed with irreversible pulpitis. Despite favorable success rate reported for RCT in vital cases, it is time consuming, and might increases fracture susceptibility of teeth. With the advancement of materials and better understanding of pulpal healing, vital pulp therapy is practiced as an alternative treatment with high success rate. The aim of this study is to explore the outcome, quality of life and patient satisfaction after full pulpotomy compared to RCT.

NCT ID: NCT05249231 Not yet recruiting - Caries Clinical Trials

Parental Satisfaction of Hall Technique Versus SDF in the Management of Carious Primary Molars

Start date: April 2022
Phase: N/A
Study type: Interventional

- The aim of this study is to assess parental satisfaction and duration of the procedure of Hall and silver diamine fluoride techniques in the treatment of carious primary molars with healthy pulp. - primary ourcome: parental satisfaction measurement device: four point likert scale measurement unit: 1-2-3-4 - secondary outcome: duration of the procedure measurement device: Digital chronometer measurement unit: minutes

NCT ID: NCT05236205 Not yet recruiting - Caries Clinical Trials

Antimicrobial Photodynamic Therapy as an Adjunct for Management of Deep Caries Lesions

Start date: May 30, 2022
Phase: Phase 2
Study type: Interventional

Alternatively to conventional treatments, chemo-mechanical caries removal agents can be used. A modality of treatment that has been increasing in dentistry is antimicrobial photodynamic therapy (aPDT). Bixa orellana, is being researched for application in aPDT. This protocol aims to determine the effectiveness of aPDT with Bixa orellana extract in deep caries lesions. Methods and analysis: A total of 160 teeth with deep occlusal dental caries will be selected and divided in 3 groups: G1 - control group (Caries removal with a lowspeed drill); G2 - Partial Caries Removal with Papacarie; G3 - Partial Caries Removal with Papacarie and application Bixa orellana extract (20%); G4 - Partial Caries Removal with Papacarie and application Bixa orellana extract (20%) with LED (aPDT). After treatment, all the teeth will be restored with glass ionomer cement and followed up clinically and radiographically, with evaluations at immediately, 1 week, 1, 3, 6, and 12 months. Dentin samples before and after treatment will be analyzed microbiologically. The data will be submitted to descriptive statistical analysis of the association between the categorical variables using the chi-square test and Fisher exact text. The Student t test and analysis of variance will be used for the comparison of mean signs and symptoms of reversible pulpitis. Pearson correlation coefficients will be calculated for the analysis of correlations among the continuous variables.

NCT ID: NCT05221749 Terminated - Clinical trials for Microbial Colonization

The Antibacterial Effect of Nanosilver Fluoride on Primary Teeth

Start date: March 15, 2022
Phase: Phase 3
Study type: Interventional

To assess the antibacterial effect of Nanosilver Fluoride (NSF) in relation to caries activity in dentin caries lesions of primary teeth in comparison to Silver Diamine Fluoride (SDF).

NCT ID: NCT05212142 Completed - Caries Clinical Trials

A Strategy to Prevent the Recurrence of Dental Disease in Children Receiving Dental Treatment With General Anesthesia

Start date: June 10, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the effectiveness of a preventive strategy in increasing return to follow up and recall appointments.

NCT ID: NCT05211843 Recruiting - Caries Clinical Trials

Saliva Insulin as Biomarker of Risk Factors for Metabolic Dysregulation and Caries

Start date: October 12, 2022
Phase: N/A
Study type: Interventional

Saliva insulin shows promise as a non-invasive biomarker of high carbohydrate intake and/or insulin resistance, key risk factors for metabolic dysregulation and caries. Saliva insulin monitoring could potentially inform the planning and evaluation of interventions to prevent child obesity, diabetes and caries, without relying on self-reported measures from children, parents, child care providers or teachers. School-based public health screening programs, which have staff and data collection infrastructure in place to regularly and systematically collect saliva during oral health screening, have opportunity to monitor saliva insulin. This randomized controlled trial explores if saliva insulin is responsive to the kinds of obesity and caries intervention currently in progress in schools, namely drinking water intervention. Public health programs may justify adding saliva collection to protocol already in place if saliva insulin data are found to be actionable, i.e. sensitive to risk and intervention.