Identification of Risk Factors for Cardiovascular Disease and Cancer in Korean Population: A Prospective Cohort Study

Cardiovascular Diseases Clinical Trial

Official title:

Identification of Risk Factors for Cardiovascular Disease and Cancer in Korean Population: A Prospective Cohort Study

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05389956
• Other study ID #: 2021-12-014-003
• Status: Recruiting
• Start date: January 1, 2023
• Est. completion date: August 2052

Study information

• Verified date: March 2024
• Source: Ulsan University Hospital
• Contact: Sangwoo Park, MD
• Phone: 82-52-250-8669
• Email: warya7[@]naver.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Cancer and cardiovascular disease are the global leading causes of death. These two disease entities are multifactorial disease that are caused by several factors. The aim of this prospective cohort study was to investigate the status of risk factors profiles and health related behavior in Korean population, and to discover novel risk factors associated with the occurrence of endpoint events.

Description:

This is a single center, observational, prospective cohort study. The primary outcomes include the incidence of MACE (major adverse cardiovascular events) and the incidence of any malignancy. We plan to collect the baseline information at enrollment and the occurrence of clinical endpoint events will be followed for at least 10 years. The study will enroll 510,000 subjects aged ≥19 years who underwent a general health screening in Korea.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 510000
• Est. completion date: August 2052
• Est. primary completion date: August 2042
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 19 Years and older

Eligibility

Inclusion Criteria:

• Men or women aged 19 years and older who underwent a general health screening at the health promotion center of Ulsan University Hospital (Ulsan, Korea)

• Subjects have to agree to participate by signing a consent

Exclusion Criteria:

• Subjects who cannot or reject to sign the consent form.

Related Conditions & MeSH terms

• Cardiovascular Diseases
• Malignancy
• Neoplasms
• Risk Factor

Locations

Country	Name	City	State
Korea, Republic of	Ulsan University Hospital	Ulsan

Sponsors (1)

Lead Sponsor	Collaborator
Ulsan University Hospital

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Major adverse cardiovascular event (MACE)	A major adverse cardiovascular event (MACE) of cardiovascular death, nonfatal myocardial infarction, and nonfatal stroke	10 year
Primary	Incidence of malignancy	The occurrence of any malignancy of interest	10 year
Secondary	All-cause death		10 year
Secondary	Cardiovascular death		10 year
Secondary	Myocardial infarction		10 year
Secondary	Stroke		10 year
Secondary	Cancer related mortality		10 year