Impact of Periodontal Treatment on Local miRNA Expression

Status Completed

Clinical Trial Summary

To assess the impact of Fill Mouth Scaling and Root planing or Quadrant Scaling and Root planing gingival crevicular fluid (GCF) levels of miRNA 7a-5p, miRNA 21-3p, miRNA 21-5p, miRNA 100-5p, miRNA 125-5p, miRNA 200b-3p and miRNA 200b-5p and their correlation with periodontitis extent.

Clinical Trial Description

The patients selected for the study were divided into 2 groups: group 1 (FM-SRP), group 2 (Q-SRP). Any selected subject underwent anamnestic and periodontal examination, blood and GCF sampling. MiRNA in the GCF was extracted through a commercially available kit and then measured carrying out real-time quantitative polymerase chain reaction (RT-PCR). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05275127
Study type	Observational
Source	University of Catania
Contact
Status	Completed
Phase
Start date	March 14, 2022
Completion date	November 20, 2022

View Details

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