Cardiovascular Diseases Clinical Trial
Official title:
Cardiovascular Mechanisms of the Occupational Physical Activity Health Paradox: 24-hour Physical Activity, Blood Pressure, and Heart Rate
Verified date | April 2021 |
Source | University of Pittsburgh |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
This is an observational study to examine the cardiovascular mechanisms of increased cardiovascular mortality in those with high activity occupations.
Status | Completed |
Enrollment | 19 |
Est. completion date | July 24, 2020 |
Est. primary completion date | April 20, 2020 |
Accepts healthy volunteers | |
Gender | Male |
Age group | 35 Years to 59 Years |
Eligibility | Inclusion Criteria: - middle age (35-59 years) - male - self-report working full-time in the food service industry (=30 hours/week) - self-report predominantly completing light intensity activity job responsibilities (=75% work time walking, light movement, or standing) Exclusion Criteria: - Resting blood pressure of =150 mmHg systolic and/or =95 mmHg diastolic - currently taking medications that are known to affect blood pressure or heart rate (e.g. Beta-blockers, ACE inhibitors, etc.) - greater than low risk to participate in physical activity as determined by PAR-Q (answer of yes to any of the 7 physical activity readiness questionnaire questions) - report working a second job in addition to their primary full-time job - report working overnight shifts (10pm-6am) - reported physical dysfunction (inability to walk 2 city blocks or climb 2 flights of stairs) - inability to complete the sub-maximal exercise test to completion (80% age-predicted heart rate maximum) - Currently being treated for a serious medical condition such as kidney disease, liver disease, cancer, or heart disease. |
Country | Name | City | State |
---|---|---|---|
United States | Physical Activity and Weight Management Research Laboratory | Pittsburgh | Pennsylvania |
Lead Sponsor | Collaborator |
---|---|
University of Pittsburgh |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | 24-hour Heart Rate | We will calculate the average heart rate over each 24 hour period throughout a one week monitoring period. | 24 hours | |
Secondary | 24-hour Ambulatory Systolic Blood Pressure | We will calculate the average systolic blood pressure over a 24-hour period on two separate days (workdays versus non-workdays). | 24 hours | |
Secondary | Nocturnal Heart Rate Variability, RMSSD | We will calculate the average heart rate variability during each night's sleep for a total of one week. The specific HRV variable presented is root mean square successive differences (RMSSD). | approximately 8 hours (sleep time) | |
Secondary | Physical Activity Pattern. Steps Per Day | This physical activity metric of steps per day was calculated as average number of steps during each day type (work versus non-workdays) throughout one week | 1 week | |
Secondary | Nocturnal Heart Rate Variability, SDNN | We will calculate the average heart rate variability during each night's sleep for a total of one week. The specific HRV variable presented is standard deviation of the normal to normal RR intervals (SDNN). | approximately 8 hours (sleep time) | |
Secondary | Nocturnal Heart Rate Variability, LF | We will calculate the average heart rate variability during each night's sleep for a total of one week. The specific HRV variable presented is low frequency power (LF). | approximately 8 hours (sleep time) | |
Secondary | Nocturnal Heart Rate Variability, HF | We will calculate the average heart rate variability during each night's sleep for a total of one week. The specific HRV variable presented is high frequency power (HF). | approximately 8 hours (sleep time) | |
Secondary | Physical Activity Pattern. MVPA | This physical activity metric of minutes of moderate to vigorous physical activity was calculated as average minutes during each day type (work versus non-workdays) throughout one week | 1 week | |
Secondary | Physical Activity Pattern. LPA | This physical activity metric of minutes of light physical activity was calculated as average minutes during each day type (work versus non-workdays) throughout one week | 1 week | |
Secondary | Physical Activity Pattern. Sedentary | This physical activity metric of minutes of sedentary time was calculated as average minutes during each day type (work versus non-workdays) throughout one week | 1 week | |
Secondary | Physical Activity Pattern. Upright | This physical activity metric of minutes of upright time was calculated as average minutes during each day type (work versus non-workdays) throughout one week | 1 week | |
Secondary | 24-hour Ambulatory Diastolic Blood Pressure | We will calculate the average diastolic blood pressure over a 24-hour period on two separate days (workdays versus non-workdays). | 24 hours |
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