SWAP-MEAT: Study With Appetizing Plant Food - Meat Eating Alternatives Trial — SWAP-MEAT  

Cardiovascular Diseases Clinical Trial

Official title: SWAP-MEAT: Study With Appetizing Plant Food - Meat Eating Alternatives Trial

Status Completed

Clinical Trial Summary

This study aims to investigate the impact of replacing meat consumption with plant-based meat alternative consumption on cardiovascular health, the gut microbiome, and metabolic status.

Clinical Trial Description

Plant-based meat alternatives that closely emulate animal protein provide a new opportunity to decrease meat consumption worldwide. Decreasing meat consumption and shifting to a plant-based diet has been linked to improvements in physical health, including decreased risk of cardiovascular disease, metabolic syndrome, and type 2 diabetes (Kahleova, Levin, & Barnard, 2017). However, the extent to which plant-based meat alternatives specifically can modulate biomarkers of physical health, particularly TMAO and IGF-1, and the gut microbiome remain relatively unexplored. It is also largely unknown to what extent consumers can feasibly and sustainably exchange meat products for plant-based meat alternatives for extended periods of time. Plant-based meat alternatives offer a promising way to support consumers' shift to a plant-based diet, and in turn, to potentially improve levels of TMAO and IGF-1 and decrease cardiovascular risk. Thus, the investigators hypothesize that consumer levels of TMAO and IGF-1 will be improved after 8 weeks of consuming plant-based meat alternative products, as compared to 8 weeks of consuming traditional meat products. ;

Related Conditions & MeSH terms

• Cardiovascular Diseases
• Immune Function
• Microbiome

• NCT number: NCT03718988
• Study type: Interventional
• Source: Stanford University
• Status: Completed
• Phase: N/A
• Start date: January 17, 2019
• Completion date: December 5, 2019