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Feeding the Rainbow to Investigate Endothelial Dysfunction — FRIED  

Cardiovascular Disease Clinical Trial

Official title:
Evaluating the Effects of Mixed-Carotenoids on Biomarkers of Endothelial Dysfunction

Clinical Trial Summary

The primary purpose of this study is to compare the change in blood carotene concentration between a food-based versus nutritional supplement-based intervention. This study will randomize up to 60 healthy volunteers to receive either carotenoid-enriched food; natural, mixed carotenoid supplementation; chlorophyll complex or placebo supplementation. Blood carotene levels will be measured before and after 28 days of supplementation. Preliminary data will also be collected on several biomarkers associated with vascular inflammation and endothelial dysfunction. These biomarkers will be measured before and during a fast food control meal at the beginning and end of the intervention period.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Bio-equivalence Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Basic Science

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01175577
Study type Interventional
Source Bastyr University
Contact
Status Completed
Phase Phase 0
Start date October 2009
Completion date August 2011
View Details
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