The Early Origins of Cardiovascular Disease

Status Not yet recruiting

Clinical Trial Summary

Small body size at birth, slow weight gain during infancy and increase in body mass index after 2 years are independent risk factors for cardiovascular disease and the metabolic syndrome. There is a large gap in our understanding of how early growth affects the cardiovascular system. Possible mechanisms include alterations in body composition, in cardiac structure, in vascular function, in renal function and epigenetic processes.

The Objective is to determine how size at birth and growth during infancy and childhood affect: body composition, cardiac structure and function, vascular and endothelial function, renal function, metabolic status and transcriptional and epigenetic characteristics.

Clinical Trial Description

n/a

Study Design

Observational Model: Cohort, Time Perspective: Retrospective

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00923039
Study type	Observational
Source	Danone Institute International
Contact	Umberto SIMEONI, MD,PhD
Phone	33 (0)4 91 38 40 30
Email	umberto.simeoni@mail.ap-hm.fr
Status	Not yet recruiting
Phase	N/A
Start date	June 2009

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