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Early Transcranial Doppler Goal Directed Therapy After Cardiac Arrest: a Pilot Study — GOODYEAR  

Cardiac Arrest Clinical Trial

Official title:
Early Transcranial Doppler Goal Directed Therapy After Cardiac Arrest: a Pilot Study

Clinical Trial Summary

Hypoxic-ischaemic brain injury (HIBI) is the main cause of death in patients who are comatose after resuscitation from cardiac arrest. Current guidelines recommend to target a mean arterial pressure (MAP) above 65 mmHg to achieve an adequate organ perfusion. Moreover, after cardiac arrest, cerebral autoregulation is dysregulated and cerebral blood flow (CBF) depends on the MAP. A higher blood pressure target could improve cerebral perfusion and HIBI. Transcranial Doppler (TCD) is a non-invasive method to study CBF and its variations induced by MAP. The aim of this study is to test the feasibility of an early-goal directed hemodynamic management with TCD during the first 12 hours after return of spontaneous circulation (ROSC).

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04000334
Study type Interventional
Source Centre Hospitalier le Mans
Contact Christelle Jadeau, PD
Phone 0 (33) 2 43 43 43 43
Email cjadeau@ch-lemans.fr
Status Recruiting
Phase N/A
Start date July 29, 2020
Completion date September 2022
View Details
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