Effects of Yoga, Strength Training and Aerobic Exercise on Cognition in Adult Cancer Survivors

Cancer Clinical Trial

Official title:

Effects of Yoga, Strength Training and Aerobic Exercise on Cognition in Adult Cancer Survivors

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03650322
• Other study ID #: 18922
• Status: Completed
• Phase: N/A
• Start date: October 1, 2018
• Est. completion date: May 30, 2020

Study information

• Verified date: June 2023
• Source: University of Illinois at Urbana-Champaign
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The investigators propose to compare the effects of a 12-week, supervised, site-based group yoga intervention on cognitive function, functional fitness, and well-being in middle-aged cancer survivors. Subjects will be randomly assigned to one of three exercise conditions: a yoga group, an aerobic walking group or a strength training group. All sessions (2-3 times per week) will be led by a trained exercise leader for a total of 150 minutes of exercise each week for the 12-week intervention.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 78
• Est. completion date: May 30, 2020
• Est. primary completion date: May 30, 2020
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 30 Years to 70 Years

Eligibility

Inclusion Criteria:

• 30-70 years of age
• Cancer diagnosis
• 1 year since last cancer treatment (surgery, chemotherapy, and/or radiation)
• Not planning to receive treatment during study period
• Completion of Physical Activity Readiness Questionnaire (PAR-Q)
• Ambulatory and absence of health conditions that may be exacerbated by yoga, walking, or strength training
• Physician consent (if deemed necessary)
• Low-active, i.e. less than 150 minutes/week of moderate to vigorous exercise, no current yoga practice (including within last six months)
• Intention to remain in the Champaign-Urbana area over the study duration
• Willingness to be randomly assigned to one of the three groups (yoga, aerobic walking, strength training)
• Comfortable with reading, writing, and speaking English

Exclusion Criteria:

• Below 30 or above 70 years of age
• Cancer diagnosis of the brain
• Less than 1 year since last treatment (surgery, chemotherapy, and/or radiation) or plans to receive treatment during study
• Determined ambulatory or 'high risk' based on responses to PAR-Q
• High-active (exercising more than 150 minutes/week in the last six months)
• No consent from physician
• Intent to be away from the Champaign-Urbana area for an extended period of time during the study
• Inability to communicate effectively in English

Related Conditions & MeSH terms

• Cancer
• Cancer-related Problem/Condition
• Exercise

Intervention

Behavioral:
• Yoga
12 weeks, total of 150 minutes of exercise per week.
• Stretching and Toning
12 weeks, total of 150 minutes of exercise per week.
• Aerobic Walking
12 weeks, total of 150 minutes of exercise per week.

Locations

Country	Name	City	State
United States	University of Illinois at Urbana-Champaign	Urbana	Illinois

Sponsors (1)

Lead Sponsor	Collaborator
University of Illinois at Urbana-Champaign

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	Feasibility: Recruitment and retention rates	Proportion of participants randomized relative to total contacts, Proportion of participants who complete follow-up questionnaires,	Baseline to 12-weeks
Primary	Cognitive Function	Participants will complete part of the NIH Toolbox measures that assess cognitive function.	Change from baseline to 12 weeks will be reported
Secondary	Cardiovascular Function	Participants will complete a submaximal exercise test to reach a target heart rate within 85% of the age-predicted maximum.	Change from baseline to 12 weeks will be reported

External Links

•   Exercise Psychology Lab