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NCT number NCT03357861
Study type Observational
Source University Hospital, Grenoble
Contact Anne-Claire TOFFART, MD-PhD
Phone +33476765453
Email AToffart@chu-grenoble.fr
Status Not yet recruiting
Phase N/A
Start date February 1, 2018
Completion date May 31, 2019

Clinical Trial Summary

This work aims to describe the characteristics and methods of management of patients suffering from a solid tumor treated with immunotherapy admitted to intensive care.


Clinical Trial Description

The place of checkpoint inhibitors (anti-PD-1 and PD-L-1) is currently validated in the management of melanoma and metastatic non-small cell lung cancer. The toxicity profile is specific with adverse effects related to immunity. Some side effects (myocarditis, colitis, interstitial lung disease, etc.) can be severe and patient could be hospitalized in intensive care unit.

The question of immunotherapy's imputability in the acute disease is becoming more frequent.


Study Design


Related Conditions & MeSH terms


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