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Clinical Trial Summary

The study purpose is to establish the safety and tolerability of IMA201 in patients with solid tumors.


Clinical Trial Description

SCREENING: Patient eligibility will be determined by HLA (human leukocyte antigen) screening and the main biomarkers screening. If the patient is eligible, white blood cells will be taken during leukapheresis for the manufacture of the IMA201 product.

MANUFACTURING: IMA201 product will be made from the patient's white blood cells.

TREATMENT: Lymphodepletion with cyclophosphamide and fludarabine will occur in the days before the IMA201 infusion to improve the duration of time that IMA201 stays in the body.

After IMA201 infusion, a low dose of IL-2 will be given twice daily for a period of time.

Since this study involves gene therapy, patients will be monitored throughout the study and for up to a total of 15 years. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03247309
Study type Interventional
Source Immatics US, Inc.
Contact Rebecca Griffith-Eskew
Phone 3462045359
Email griffith-eskew@immatics.com
Status Recruiting
Phase Phase 1
Start date September 26, 2017
Completion date December 2033

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