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Two Radiation Dose Schedules of SBRT to Lung Metastases < 5cm in Dimension

Cancer Clinical Trial

Official title:
A Randomized Phase 2 Study of Two Radiation Dose Schedules of Stereotactic Body Radiotherapy (SBRT) to Lung Metastases < 5cm in Dimension

Clinical Trial Summary

30 Gy single fraction of SBRT for lung metastases will result in comparable oncologic outcomes to 18Gy in three fractions (or dosing to a BED </-100Gy at the discretion of the radiation oncologist) with respect to disease control and toxicity.

Clinical Trial Description

Using two different doses of SBRT, this study will examine the 6-month local disease control rate (LDCR) of the SBRT-treated metastasis to determine the optimum dosing for SBRT in pulmonary metastases. This will allow us to establish baseline SBRT data, from which we will develop a second trial to examine sequencing of immunotherapy with SBRT. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03029416
Study type Interventional
Source University of Kentucky
Contact
Status Withdrawn
Phase Phase 2
Start date October 26, 2017
Completion date August 9, 2018
View Details
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