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Burns clinical trials

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NCT ID: NCT00701623 Withdrawn - Burns Clinical Trials

Sodic Heparin Effectiveness of the Treatment of Burns

Heparin
Start date: June 2008
Phase: Phase 2/Phase 3
Study type: Interventional

Burns are injuries caused by agents thermal, chemical, electrical or radioactive who act in the tissue lining of the human body and may partially or totally destroy the skin and its annexes, to the deeper layers, as subcutaneous tissue, muscles, tendons and bones . Studies show that topical heparin has, in addition to the already known anticoagulant activity, anti-inflammatory properties, analgesic, and neoangiogenic, stimulating blood flow and increasing the repair of the fabric as well as the restoration of collagen and reepiteliztion. Moreover, the use of heparin reduces the need for painful medical procedures, as debridations, surgeries and transplants The intention of this work is to verify the effectiveness and safety of sodium heparin in the treatment of burns of the skin.

NCT ID: NCT00697788 Completed - Burns Clinical Trials

Dexmedetomidine Cardiovascular Safety in Pediatric Burn Patients

Start date: January 2006
Phase: Phase 2
Study type: Interventional

Dexmedetomidine is a sedative drug approved for adult patients, intubated, in intensive care units. We are studying whether this drug is cardiovascularly safe in pediatric patients who have recently been burned.

NCT ID: NCT00689650 Active, not recruiting - Burn Scar Patients Clinical Trials

Fractional Nonablative 1540 nm Laser Resurfacing for Burn Scars- A Randomised Controlled Trial

Start date: November 2007
Phase: N/A
Study type: Interventional

The objective was to evaluate the efficacy of 1540 nm fractional laser treatment of mature burn scars.

NCT ID: NCT00676013 Terminated - Burns Clinical Trials

Comparison of Skin Substitutes Used in Burn Care

Quad
Start date: December 1997
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if using a DERMAL LAYER under skin grafts: 1. will reduce scar formation of skin grafts 2. will reduce burn wound contractures 3. will improve functional outcome of joints requiring grafts Compare scarring outcome of Dermal products

NCT ID: NCT00675974 Withdrawn - Burns Clinical Trials

Use of Pressure Garments for Burn Scars

Jobst
Start date: August 2005
Phase: Phase 2/Phase 3
Study type: Interventional

1. Will Pressure Garment Therapy better control hypertrophic scarring than no Pressure Garment Therapy. 2. How will Pressure Garment Therapy affect functional capacity or scar contracture development across joints either in number or severity. 3. Will Pressure Garment Therapy diminish discomfort due to pruritus.

NCT ID: NCT00675922 Terminated - Burn Clinical Trials

Study of the Treatment of Burn Wounds With Antimicrobial Topical Soaks

Soaks
Start date: July 1995
Phase: Phase 2/Phase 3
Study type: Interventional

Determine effectiveness of various antimicrobial solutions on burn wounds (infections, wound healing, length of hospital stay).

NCT ID: NCT00675714 Terminated - Burns Clinical Trials

Assessment of the Treatment of Severely Burned With Anabolic Agents on Clinical Outcomes, Recovery and Rehabilitation

Start date: January 2004
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of the program is to study and characterize the outcome of burn injury with particular attention to improving the rehabilitation of burn survivors, including children. Various agents are assessed for effectiveness on long term burn outcome, such as growth hormone, oxandrolone, propranolol,ketoconazole, inhospital exercise and home exercise.

NCT ID: NCT00674999 Withdrawn - Burn Clinical Trials

Use of Amnion on Partial Thickness Burns

Amnion
Start date: June 2005
Phase: Phase 2/Phase 3
Study type: Interventional

To determine if Amnion, used on partial thickness burn injuries would provide an improvement in rate of healing, pain control and scarring as compared to standard medical treatments.

NCT ID: NCT00673309 Completed - Burns Clinical Trials

Assessment of Mechanisms of Improved Wound Healing

Start date: July 2000
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to find ways to improve wound healing and decrease the negative effects of trauma from burn injury.

NCT ID: NCT00671307 Completed - Infection Clinical Trials

Ascending Single Dose Study of Rhu-pGelsolin in Patients With Decreased Gelsolin Levels

Start date: March 2008
Phase: Phase 1/Phase 2
Study type: Interventional

This study is designed to assess the pharmacokinetics and safety of an infusion of a single dose of recombinant plasma gelsolin (rhu-pGelsolin) when given to patients admitted to the Intensive Care Unit with documented low levels of natural gelsolin. It is believed that this drug will raise the gelsolin levels in these patients and decrease the probability that they will develop complications from their underlying disease such as organ system failure or death.