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Burns clinical trials

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NCT ID: NCT02712580 Not yet recruiting - Burns Clinical Trials

Therapeutic Effect of the Wireless Micro Current Stimulation in Pediatric Deep Dermal Burns and Scald Injuries

ELSTHER
Start date: April 2016
Phase: N/A
Study type: Interventional

This study will determine the effect of the wireless micro current stimulation in pediatric deep dermal burns and scald injuries. The clinical trial ist designed as a blinded, placebo-controlled, randomized, prospective, single-center study.

NCT ID: NCT02712164 Withdrawn - Burns Clinical Trials

Molecular, Histologic, and Clinical Analysis of Negative Pressure Wound Therapy (NPWT) for Split-thickness Skin Graft (STSG) Donor Sites

Start date: July 2017
Phase: N/A
Study type: Interventional

The purpose of this single-center, randomized, prospective cohort study is to evaluate the clinical outcome and negative-pressure wound therapy (NPWT) mediated modulation of the biologic milieu of a modified NPWT dressing on split-thickness skin graft (STSG) donor sites.

NCT ID: NCT02707627 Completed - Burns Clinical Trials

Laser Therapy for Pediatric Burn Scars

Start date: October 2016
Phase:
Study type: Observational

A new era of outcomes for pediatric burn patients has begun as burn care continues to improve. Unfortunately, complete restoration of burn-injured skin may be limited by the development of hypertrophic scarring. Treatment with laser therapy is one of the newest forms of scar therapy available. Although laser therapy has only been adopted by burn clinicians within the last several years, early evidence suggests that it may offer significant benefits. Thus the aim of this study is to investigate the effectiveness of using laser therapy to treat hypertrophic burn scars in pediatric patients by using a comprehensive set of subjective and objective scar assessment tools.

NCT ID: NCT02693249 Completed - Burns Clinical Trials

Dysfunctional Posttraumatic Cognitions in Children and Adolescents

PTC
Start date: February 2016
Phase:
Study type: Observational

The purpose of this study is to investigate the psychological consequences of motor vehicle accidents and burn accidents in 7-18 years old children and adolescents. The impact of posttraumatic cognitions on developing psychological symptoms are of particular interest.

NCT ID: NCT02691650 Completed - Trauma Clinical Trials

Point of Care Testing of Cholinesterase Activity During Burn- and Polytrauma

POCCET
Start date: February 2016
Phase:
Study type: Observational

Goal of this study is to measure serum cholinesterase activity in patients with traumatic and/or burns injury admitted to the emergency room by using point-of- care-test system (POCT). Serum cholinesterase activity, measured using POCT system, might play an important role in the early diagnosis and prediction of patient outcome in trauma-induced systemic inflammation.

NCT ID: NCT02690844 Withdrawn - Clinical trials for Burning Mouth Syndrome

Effectiveness of Mucolox® and Clonazepam in Treatment of Burning Mouth Syndrome

Start date: April 2016
Phase: Phase 4
Study type: Interventional

What affect does the use of a mucoadhesive drug delivery system (Mucolox®) compounded with clonazepam have in the treatment of burning mouth syndrome? There are no clinical trials reported in the literature that evaluate the use of a mucoadhesive vehicle to deliver clonazepam into the oral cavity and treat burning mouth syndrome. The use of a mucoadhesive may help to increase surface contact and elicit a greater reduction in symptoms.

NCT ID: NCT02689713 Withdrawn - Pain Clinical Trials

Pilot Study to Compare Topical Voriconazole to Placebo as a Pain Reducing Agent

Start date: June 15, 2018
Phase: Phase 2
Study type: Interventional

This study seeks to test if the study drug (voriconazole), when applied topically to a burn wound on the skin will help to reduce pain.

NCT ID: NCT02686359 Completed - Clinical trials for Burning Mouth Syndrome

Opiorphin Levels in Fluids of Burning Mouth Syndrome Patients (OPIODYN)

OPIODYN
Start date: July 2011
Phase: N/A
Study type: Interventional

If epidemiological studies indicate relatively low prevalence reported in the general population, idiopathic burning mouth syndrome (BMS) is a common condition among certain groups of the population: 30% of menopausal women experience oral burning to varying degrees . Despite significant progress made in recent years, in understanding the physiopathogeny, treatment options remain limited and disappointing,resulting in an impairment of the quality of life. Given the chronic nature of idiopathic burning mouth syndrome, the need to identify the causes and effective treatment modalities for subjects suffering is essential.

NCT ID: NCT02684669 Completed - Healthy Subjects Clinical Trials

Effect of High-dose Target-controlled Naloxone Infusion on Pain and Hyperalgesia During a Burn Injury

TCI-NX-BI
Start date: February 2016
Phase: Phase 2
Study type: Interventional

In several rodent studies, it has been demonstrated that very high doses of opioid antagonists (i.e., naloxone 3-10 mg/kg) administered after weeks after recovery from an inflammatory injury may lead to a reinstatement of hyperalgesia and pain behavior. This latent sensitization has recently been demonstrated also to take place in humans. The present study examines if it is possible to foresee individuals who will demonstrate a larger degree of latent sensitization upon challenge with an injury, than others. Using an enriched design high sensitizers (e.g., the upper quartile of individuals developing large areas of secondary hyperalgesia following a mild burn injury) are compared with low sensitizers (lower quartile), regarding the propensity for developing latent sensitization

NCT ID: NCT02681757 Completed - Burns Clinical Trials

Comparison of Mepitel Ag vs Antibiotic Ointment Used With Soft Cast Technique for Treatment of Pediatric Burns

Start date: September 2016
Phase: N/A
Study type: Interventional

The aim of this study is to compare Mepitel Ag to Triple antibiotic ointment impregnated Adaptic gauze when used with the soft cast technique to assess overall time to healing, yeast infection rate and parents perception of pain level at time of dressing change on a scale of 1-10. The hypothesis is that Mepitel Ag in combination with the soft cast technique improves wound healing in pediatric partial to deep partial thickness hand and foot burns by decreasing the length of healing time, decreasing the risk of yeast infection, and decreasing pain associated with dressing changes.