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Burns clinical trials

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NCT ID: NCT02689713 Withdrawn - Pain Clinical Trials

Pilot Study to Compare Topical Voriconazole to Placebo as a Pain Reducing Agent

Start date: June 15, 2018
Phase: Phase 2
Study type: Interventional

This study seeks to test if the study drug (voriconazole), when applied topically to a burn wound on the skin will help to reduce pain.

NCT ID: NCT02404597 Withdrawn - Burns Clinical Trials

Cardiac Output Monitoring in Burn Patients

Start date: January 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to describe the use of non-invasive cardiac output monitors (NICOM) in patients with burn injuries and to develop a protocol for NICOM in a burn unit.

NCT ID: NCT02318056 Withdrawn - Burns Clinical Trials

The Burn Glove Trial - Hand Burn Dressing Pilot

Start date: December 2015
Phase: N/A
Study type: Interventional

Specific Aim 1: To determine if one of three burn dressings provides a less painful healing experience for partial thickness hand. Specific Aim 2: To evaluate if one of three dressings provides greater functionality during and after healing of partial thickness hand burns. Specific Aim 3: To determine if one of three burn dressings promotes aesthetically superior healing results for partial thickness hand burns.

NCT ID: NCT02241941 Withdrawn - Burn Injury Clinical Trials

Evaluation of Single-dose Pharmacokinetics of Intravenous Daptomycin in Patients With Thermal Injury

Start date: September 2014
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine single dose pharmacokinetics of daptomycin consecutively in 10 patients on three different time points after severe burn injury.

NCT ID: NCT02029261 Withdrawn - Burn Clinical Trials

Observational Study of Insulin Resistance and Muscle Wasting After Burn Injury

Start date: May 2014
Phase:
Study type: Observational

The purpose of this study is to examine important and significant problems, that of insulin resistance and muscle wasting after burn injury.

NCT ID: NCT01922960 Withdrawn - Trauma Clinical Trials

Microcirculatory Assessment in Patients With Trauma and Severe Burns

Start date: April 7, 2012
Phase: N/A
Study type: Interventional

Predict the development of multiple organ failure in patients with trauma and severe burns.

NCT ID: NCT01911858 Withdrawn - Third Degree Burns Clinical Trials

Askina Calgitrol Paste Burns

Start date: April 2013
Phase: Phase 3
Study type: Interventional

The purpose of the study is to demonstrate that Askina® Calgitrol® Paste is safe to use on III degree burns by quantifying the concentration of silver in the blood during treatment and thus to show that the amount of silver absorbed will be no greater than those reported in the literature.

NCT ID: NCT01790763 Withdrawn - Clinical trials for Skin Burn Degree Second

Compare the Efficacy of Mepilex and Keramatrix in Second Degree Burn Wounds

Start date: April 2015
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to determine the extent to which Keramatrix dressing promotes the healing of second-degree burn wounds in pediatric patients.

NCT ID: NCT01750034 Withdrawn - Burns Clinical Trials

Best Method of Burn Wound Care: A Prospective Randomized Trial

Start date: June 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to better understand how to best care for burn wounds.

NCT ID: NCT01587261 Withdrawn - Clinical trials for Severe Thermal Injury, Greater Than 20% TBSA

Vitamin C for Severe Thermal Injuries

Start date: June 2017
Phase: Phase 2
Study type: Interventional

Animal and human data have supported the notion that administration of large doses of Vitamin C has beneficial effects on those subjects suffering from large burns. This effect may be due, in part, to the antioxidant and free-radical-scavenging properties of Vitamin C. These studies have demonstrated an improvement in urine output during resuscitation and reduced need for fluid volumes during resuscitation. In turn, these subjects demonstrated a reduction of wound edema, improved respiratory status (demonstrated by improvements in P:F ratios and reduced ventilator days), and no differences in terms of the possible complications of high-dose vitamin C administration between standard and treatment groups. The purpose of this study is to prospectively determine if Vitamin C can be safely used as an adjunctive treatment for patients suffering severe thermal injuries. High-dose vitamin C administered at a dose of 66mg/kg/hr during the acute phase of severe burn injuries will reduce fluid requirements in the first 48 hours after injury.