Study of DS-8201a, an Antibody Drug Conjugate for Advanced Breast Cancer

Clinical Trial Description

The main objective is to evaluate the anti-tumor activity of DS-8201a in three cohorts of advanced breast cancer patients: - Cohort 1: HER2 over-expressing (HER2 IHC3+ or HER2 IHC2+/ISH+) - Cohort 2: HER2 low-expressing (IHC1+ or IHC2+/ISH-) - Cohort 3: HER2 non-expressing (IHC0+) ;

Study Design

See also
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Terminated	`NCT01194908` - Re-expression of ER in Triple Negative Breast Cancers	Phase 1/Phase 2
Completed	`NCT02296801` - A Phase II Randomized Study Evaluating the Biological and Clinical Effects of the Combination of Palbociclib With Letrozole as Neoadjuvant Therapy in Post-Menopausal Women With Estrogen-Receptor Positive Primary Breast Cancer	Phase 2
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NCT number	NCT04132960
Study type	Interventional
Source	UNICANCER
Contact
Status	Active, not recruiting
Phase	Phase 2
Start date	October 21, 2019
Completion date	April 22, 2025

Study of DS-8201a, an Antibody Drug Conjugate for Advanced Breast Cancer Patients, With Biomarkers Analysis — DAISY

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms