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Clinical Trial Summary

This study will evaluate the recommended dose for further clinical development, safety, tolerability, anti-tumor activity, immunogenicity, pharmacokinetics and pharmacodynamics of IKS014, a HER2 targeting antibody-drug conjugate, in patients with advanced solid tumors.


Clinical Trial Description

The study will consist of 2 parts: dose-escalation (Part 1) and dose-expansion (Part 2). The dose-escalation part (Part 1) of the study is to evaluate the safety and tolerability of increasing dose levels of IKS014 to establish a recommended phase 2 dose (RP2D); and the dose-expansion part (Part 2) of the study is to further evaluate the safety, pharmacokinetics/pharmacodynamics, and efficacy of IKS014 at the RP2D. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05872295
Study type Interventional
Source Iksuda Therapeutics Ltd.
Contact David Browning
Phone +1-615-975-7776
Email david.browning@iksuda.com
Status Recruiting
Phase Phase 1
Start date September 14, 2023
Completion date September 2027

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