Breast Cancer Female Clinical Trial
Official title:
The Impact of Different Physical Exercise Protocols on Cardio-vascular Efficiency and Quality of Life in Breast Cancer Survivors
To examine the effects of different physical exercise protocols (aerobic training and resistance training) on cardio-vascular efficiency and quality of life in a population of breast cancer survivors (BCS), not treated with chemotherapy.
The present study enrolled a population of BCS women who underwent surgical treatment for
breast cancer at the "Ospedale G. Bernabeo" of Ortona, Chieti, Italy. The participants were
randomized to the following physical exercise protocols: aerobic training, walking or Nordic
walking; resistance training.
All the participants have been examined utilizing transthoracic echocardiography, carotid
ultrasound and photo-plethysmographic method for the analysis of arterial stiffness, before
and after the physical exercise protocol (T0-T1). The two-dimensional speckle-tracking
analysis was performed with an offline, dedicated software from the apical 4-chambers-view.
Moreover, ventricular-arterial coupling, epicardial fat thickness and intima-media thickness
were also analyzed.
Quality of life was assessed using SF-36 score at T0, T1 and at a mean follow-up of 34
months. Moreover, at follow-up, we evaluated spontaneous physical activity and cardiovascular
quality of life using IPAQ and SAQ-7 scores.
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