Breast Cancer Female Clinical Trial
Official title:
Hormone Therapy Initiation Immediately After Histological Diagnosis of Breast Cancer, Can it Make Any Difference?
Breast Cancer is a public health issue worldwide. The time from diagnosis to treatment
initiation varies from country to country and regionally within a country. Early diagnosis
and prompt treatment initiation are key factors in patient survival rates.
Currently there is a rising trend, with a high percentage of patients with "Luminal" like
breast cancer only undergoing adjuvant endocrine therapy.
Authors argue that tumor biology alterations after introducing very early endocrine therapy
might have a prognostic and therapeutic impact and should be studied.
Selected patients of female gender, above 50 y.o, and after a biopsy of Luminal-like Breast
Cancer will go under aromatase inhibitor, from the diagnosis day till the surgical therapy to
be decided (if so).In this study are going to be included patients that refuse surgical
treatment, remaining this way in an "active surveillance". This last group is going to be
randomised in order to recieve hormontherapy plus placebo vs hormontherapy plus
acetolisalicilic acid.
In this way, authors want to investigate if:
1. st This approach influences the tumor biology
2. nd This approach influences tumor pathologic response and progression free survival.
3. rd It is a valid approach and in which grade, for patients that refuse surgical
treatment
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