Breast Cancer Clinical Trial
Official title:
Cognitive Enhancement Program
This randomized clinical trial studies cognitive enhancement program in improving cognitive function in breast cancer survivors. A cognitive enhancement program may help improve cognitive function in breast cancer survivors and may help doctors plan better treatment for cognitive decline.
PRIMARY OBJECTIVES:
I. To improve cognition of women who have had breast cancer and exhibit cognitive decline
through a cognitive enhancement program.
OUTLINE: Participants are randomized to 1 of 2 arms.
ARM I (Cognitive Enhancement Program): Participants are randomized to 1 of 2 arms.
ARM IA (Lumosity): Participants complete Lumosity cognitive exercises. Lumosity cognitive
exercises are online video game-based activities that are designed to practice various
cognitive skills including processing speed, attention, memory and executive function.
Participants complete cognitive exercises at least 20 minutes a day, 5 days a week for 6
weeks. Participants also complete relaxation exercises (guided imagery, progressive muscle
relaxation, and/or autogenics) at least 10 minutes a day for 6 weeks and compensatory
strategies (the use of external devices such as a notebook, day planner, or smartphone for
cuing, reminding, and organizing; the use of memory strategies such as repetition,
paraphrasing, and active listening; and the use of executive strategies such as self-talk
for planning and attention orientation) as much as possible.
ARM IB (Active Journaling): Participants complete Active Journal cognitive exercises. Active
Journaling requires participants to keep a written diary or journal where she discusses what
her thoughts and feelings about various events with a focus on describing the meaning of the
activities and experiences, particularly new things that were learned. Active Journaling is
a method of practicing various cognitive skills including communication, organization,
memory and executive function. Participants complete cognitive exercises at least 20 minutes
a day, 5 days a week for 6 weeks. Participants also complete relaxation exercises and
compensatory strategies as in Arm IA.
ARM II (Lumosity only): Participants complete Lumosity cognitive exercises as in Arm IA.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Supportive Care
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