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Apatinib With CDK4/6 Inhibitor and Endocrine Therapy in HR+/ HER2- Advanced Breast Cancer

Breast Cancer Metastatic Clinical Trial

Official title:
Apatinib in Combination With CDK4/6 Inhibitor and Endocrine Therapy as the First-line Therapy for HR+/ HER2-Advanced Breast Cancer

Clinical Trial Summary

This study is a prospective, open-label, phase II clinical study for patients with HR+/HER2- advanced breast cancer.

Clinical Trial Description

Patients with SNF34subtype of HR+/HER2- advanced breast cancer confirmed by the Department of Pathology and Key Laboratory of Breast Cancer of Fudan University Affiliated Cancer Hospital are planned to be enrolled. The main purpose is to evaluate efficacy of Apatinib in SNF4 subtype of HR +/HER2- advanced breast cancer and prepare for subsequent randomized controlled phase III clinical studies with larger sample size. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05759572
Study type Interventional
Source Fudan University
Contact Zhimin Shao
Phone 86-021-64175590
Email zhimingshao@yahoo.com
Status Recruiting
Phase Phase 2
Start date February 1, 2023
Completion date June 1, 2027
View Details
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