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Cancer/Testis Antigen Immunotherapy Phase I Study With 740-CTA Vaccinia Virus — rVV-740CTA  

Breast Carcinoma Clinical Trial

Official title:
Monocentric Open Label Phase I Immunotherapy Trial of Breast Cancer Patients With a Non-replicating Recombinant Vaccinia Virus Expressing Cancer/Testis Antigens and Cluster of Differentiation Antigen 80 (CD80)-CD40L Costimulatory Molecules.

Clinical Trial Summary

Monocentric open-label phase I/II trial aiming at evaluating, in adjuvant setting, safety (primary outcome), immunological and clinical efficacy (secondary outcomes) of a non replicating recombinant vaccinia virus expressing cancer/testis antigen (CTA) derived epitopes and CD80 and CD40 ligand (CD40L, CD154) costimulatory molecules in patients with CTA expressing tumors.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03110445
Study type Interventional
Source University Hospital, Basel, Switzerland
Contact
Status Withdrawn
Phase Phase 1
Start date March 2020
Completion date September 2021
View Details
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