Brain Ischemia Clinical Trial
— PROMPTSOfficial title:
PROgnostic Value of MicroParticles and Markers of Hemostasis in TIA and Ischemic Stroke
NCT number | NCT05524506 |
Other study ID # | KIDS-IM-LL-2016-01 |
Secondary ID | |
Status | Completed |
Phase | |
First received | |
Last updated | |
Start date | June 2007 |
Est. completion date | June 30, 2021 |
Verified date | August 2022 |
Source | Karolinska Institutet |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
The purpose is to investigate if different microparticles and markers of hemostasis predict outcome after TIA or ischemic stroke and to study the association between these variables and stroke subtype or etiology.
Status | Completed |
Enrollment | 249 |
Est. completion date | June 30, 2021 |
Est. primary completion date | December 2014 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 45 Years and older |
Eligibility | Cohort established in NTC01160406 Inclusion Criteria: - acute ischemic stroke or TIA less than 2 weeks before enrollment - ability to understand study instructions both verbal and written - ability to handle handheld ECG Exclusion Criteria: - known atrial fibrillation - hemorrhagic stroke at time of enrollment - limited compliance - pacemaker |
Country | Name | City | State |
---|---|---|---|
Sweden | Karolinska Institutet, Daderyd Hospital | Stockholm |
Lead Sponsor | Collaborator |
---|---|
Karolinska Institutet | Danderyd Hospital, Stockholm South General Hospital |
Sweden,
Lundström A, Änggårdh-Rooth E, Mobarrez F, Thålin C, Gigante B, Laska AC, Wallén H. High Thrombin Generation after Acute Ischemic Stroke or Transient Ischemic Attack Is Associated with a Reduced Risk of Recurrence: An Observational Cohort Study. Thromb Haemost. 2021 May;121(5):584-593. doi: 10.1055/s-0040-1721146. Epub 2020 Dec 12. — View Citation
Lundström A, Mobarrez F, Rooth E, Thålin C, von Arbin M, Henriksson P, Gigante B, Laska AC, Wallén H. Prognostic Value of Circulating Microvesicle Subpopulations in Ischemic Stroke and TIA. Transl Stroke Res. 2020 Aug;11(4):708-719. doi: 10.1007/s12975-019-00777-w. Epub 2020 Jan 25. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Fatal or non-fatal ischemic stroke or myocardial infarction. | New fatal or non-fatal ischemic stroke after the initial ischemic stroke or TIA leading to recruitment. Outcome events and time of events are extracted from national registries ('Patientregistret', 'Dödsorsaksregistret') and hospital records. | 2007-2014 | |
Secondary | Recurrent ischemic stroke | Recurrent ischemic stroke (fatal or non-fatal) after initial ischemic stroke or TIA leading to recruitment. Outcome events and time of events are extracted from national registries ('Patientregistret') and hospital records. | 2007-2014 | |
Secondary | All-cause mortality | All cause mortality after initial ischemic stroke or TIA leading to recruitment. Outcome events and time of events are extracted from national registry ('Dödsorsaksregistret'). | 2007-2014 |
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