Remote Ischemic Preconditioning on Brain Injury in Carotid Endarterectomy

Status Recruiting

Clinical Trial Summary

This is a randomized controlled trial designed to test an intervention (Remote ischemic preconditioning) in patients undergoing carotid endarterectomy (CEA).Remote ischemic preconditioning(RIPC) with transient upper limb ischemia/reperfusion is a novel, simple, cost-free,non-pharmacological and non-invasive strategy.The purpose of this study is to evaluate the effects of Remote Ischaemic Preconditioning on perioperative ischaemic injury in patients undergoing carotid endarterectomy compared to control intervention.The outcomes of interest include neurocognitive function,clinical outcomes,and biomarkers of brain injury.

Clinical Trial Description

Remote ischemic preconditioning (RIPC) protocol will be induced during anesthesia by 3 cycles of 5-min upper limb ischemia and 5-min reperfusion using a blood pressure cuff inflated to a pressure 200mmHg ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03027011
Study type	Interventional
Source	The Affiliated Hospital of Xuzhou Medical University
Contact	Chen Xiuxia, MD
Phone	+86-18052268332
Email	cxxlxy@sina.com
Status	Recruiting
Phase	N/A
Start date	March 1, 2017
Completion date	December 2017

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