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Bowel Preparation clinical trials

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NCT ID: NCT04434625 Completed - Colonoscopy Clinical Trials

The Effect of a Predictive Model of Bowel Preparation Based on Procedure-related Factors

Start date: June 14, 2020
Phase: N/A
Study type: Interventional

The rate of adequate bowel preparation is one of important quality indicators of colonoscopy. Inadequate bowel preparation negatively affects the outcomes of colonoscopy. If patients with inadequate bowel preparation were identified before the procedure, enhanced strategy could be offered to achieve better bowel cleaning. Currently, there were three predicting models of inadequate bowel preparation established based on patient-related factors. So far, none of predictive models have been tested in other than their validation cohort populations, and no study has attempted to apply a different regimen to patients presenting with risk factors for inadequate colon cleanliness. In previous studies, we established a prediction model based on procedure-related factors, which has better accuracy and can better predict the quality of bowel preparation. The aim of this study is to compare the quality of bowel preparation by using a predictive model based on procedure-related factors versus the criterion group in unsedation patients

NCT ID: NCT04325139 Completed - Colonoscopy Clinical Trials

External Validation of a Predictive Model for Bowel Preparation in Patients Undergoing Colonoscopy

Start date: March 23, 2020
Phase:
Study type: Observational [Patient Registry]

Bowel preparation is closely lined to the quality of colonoscopy, inadequate bowel preparation (IBP) could lead to higher miss rate of adenomas, patients' discomfort and higher health expense. For the patients with possible IBP before the examination, it may be better to cancel the colonoscopy and repeat bowel preparation through modified or enhanced strategies. This study aimed to externally validate the efficiency of a procedure-based model in predicting inadequate bowel preparation

NCT ID: NCT04310332 Completed - Colonoscopy Clinical Trials

1L- vs. 4L-PEG for Bowel Preparation Among Inpatients.

Start date: February 1, 2019
Phase:
Study type: Observational

Background and aims: Inpatients are at high risk for inadequate colon cleansing. Experts recommend 4L-polyethylene-glycol (PEG) solution because of its effectiveness and safety profile. A higher colon cleansing adequacy rate for a hyperosmolar 1L-PEG plus ascorbate prep has been recently reported in an observational study among more than 1,000 inpatients. Thus, the present study is aimed at determining whether 1L-PEG outperforms 4L-PEG among inpatients, through a propensity score-matching between the two groups in order to correct for confounders.

NCT ID: NCT04247386 Completed - Bowel Preparation Clinical Trials

Mizone vs Water for Bowel Preparation.

Start date: December 25, 2019
Phase: N/A
Study type: Interventional

In order to analyze the effectiveness and patient tolerance of the two bowel preparation regimens, we will compare Polyethylene Glycol Electrolytes Powder (PEG-4000) and Mizone with PEG-ELS. The aim was to demonstrate that polyethylene glycol electrolyte powder (PEG-4000) and Mizone is not inferior in overall quality of intestinal preparation to PEG-ELS in subjects undergoing colonoscopy.

NCT ID: NCT04160104 Recruiting - Colonoscopy Clinical Trials

Pre-procedure Modle Predicts Bowel Preparation Quality Prior Colonoscopy

Start date: April 1, 2019
Phase:
Study type: Observational [Patient Registry]

Bowel preparation is closely llined to the quality of colonoscopy, inadequate bowel preparation (IBP) could lead to higher miss rate of adenomas, patients' discomfort and higher health expense. For the patients with possible IBP before the examination, it may be better to cancel the colonoscopy and repeat bowel preparation through modified or enhanced strategies. Thus, it is important to set up a model to predict the quality of bowel preparation individually.

NCT ID: NCT04113382 Recruiting - Bowel Preparation Clinical Trials

Study Assessing CLENPIQ as Bowel Preparation for Pediatric Colonoscopy

PICCOLO
Start date: June 23, 2022
Phase: Phase 1/Phase 2
Study type: Interventional

Bowel preparation for pediatric colonoscopy.

NCT ID: NCT04101097 Completed - Colonoscopy Clinical Trials

Training and Validation of Models of Factors to Predict Inadequate Bowel Preparation Colonoscopy

Start date: September 3, 2019
Phase:
Study type: Observational

The rate of adequate bowel preparation is one of important quality indicators of colonoscopy. Inadeqaute bowel preparation negatively affects the outcomes of colonoscopy. If patients with inadequate bowel preparation were identified before the procedure, enhanced strategy could be offerred to achieve better bowel cleasing. Currently, there were three predicting models of inadequate bowel preparation eatablished based on patient-related factors. It remains unclear which model perfroms better in predicting bowel preparation quality. Futhermore, althought those predicting models only composing of patients-related factors are useful for identifing high-risk patients, the preparation-related factors may also be valuable for prediciting inadeqaute bowel preparation before the procedure of colonoscopy. This study aimed: 1) to compare the values of three availlable models (based on patient-related factors) in predicting inadeqaute bowel preparation in a prospective, multicentered cohort of patients undergoing colonoscopy; 2) to investigate whether a new model based on preparation-related or a combined model based on patient-related and preparation-related factors is comparable to previous models based on patient-related factors.

NCT ID: NCT04087265 Withdrawn - Bowel Preparation Clinical Trials

Accuracy of Trans-abdominal Ultrasound in Evaluating Bowel Preparation Adequacy Before Colonoscopy

Start date: October 15, 2020
Phase: N/A
Study type: Interventional

Adequate preparation of the large bowel is required for a successful colonoscopy. It has been reported that poor preparation exists in 25% of examinations, which may lengthen overall procedure time, lower adenoma detection rate, and lead to earlier repeated colonoscopy. Evaluating the large intestine preparation by transabdominal ultrasonography can be a helpful way to predict the quality of the colonoscopy before initiating the process and therefore prevent performing the procedure in case of inadequate preparation. Estimating the colon preparation using an easy, fast and low cost way as transabdominal ultrasound before performing the colonoscopy would help the physician determine the next step. In case of poor preparation, colonoscopy can be postponed and the patient can be saved from repeated colonoscopy. The aim of this is to determine the accuracy of transabdominal ultrasonography in evaluating bowel preparation adequacy before performing colonoscopy.

NCT ID: NCT04021979 Not yet recruiting - Bowel Preparation Clinical Trials

Effectiveness of Enteral Nutrition for Dose Reduction of Low Dose PEG

Start date: August 1, 2019
Phase: N/A
Study type: Interventional

This clinical trial is being conducted to assess whether dietary restriction with enteral nutrition prescribed could prevent nonadherence to dietary restrictions, enable additional reduction of the required volume of PEG-ELS.

NCT ID: NCT03992365 Completed - Bowel Preparation Clinical Trials

Study of the Efficacy and Safety of Quiklean® and Klean-Prep With Dulcolax® for the Bowel Preparation Prior to Colonoscopy

Start date: June 10, 2019
Phase: Phase 3
Study type: Interventional

The objective is to demonstrate that investigational drug, Quiklean®, is not inferior to standard comparator, Klean-Prep with Dulcolax®, with respect to the overall quality of bowel preparation in subjects undergoing colonoscopy.