View clinical trials related to Bowel Preparation.
Filter by:Colorectal cancers are a significant global health issue, underscoring the critical importance of screening programs for early detection and effective treatment. The success of a colonoscopy is largely contingent on the quality of bowel preparation. Inadequate bowel preparation can diminish the effectiveness of a colonoscopy and lead to the oversight of lesions. Previous research has demonstrated the positive effects of diet, education, and polyethylene glycol use on bowel preparation. However, there is limited research on the impact of methods such as gum chewing and abdominal vibration. This study aims to assess the effects of gum chewing and abdominal vibration, in addition to diet and medication, on the quality of bowel preparation and patient satisfaction in the pre-colonoscopy bowel preparation process. The study employs a randomized controlled single-blind experimental design with three distinct groups: a control group, a gum chewing group, and an abdominal vibration group. Each group will be evaluated based on bowel preparation quality and patient satisfaction. Bowel preparation quality will be determined using the Boston Bowel Preparation Scale, and factors such as polyp detection, the processability of the colonoscopy, and cecal intubation time will also be assessed. Patient satisfaction levels will be evaluated by considering how satisfied patients are with the colonoscopy process, taking into account complaints before and after the procedure. The outcomes of this study will contribute to a better understanding of the impact of gum chewing and abdominal vibration on the quality of bowel preparation and patient satisfaction before colonoscopy. Identifying effective methods to enhance bowel preparation quality can elevate the standard of nursing care, contributing to a healthier society. Simultaneously, this research can improve the comfort and efficacy of the colonoscopy process for patients and enhance the effectiveness of colorectal cancer screening programs, thereby benefiting public health.
Educational interventions provided to patients may improve colon cleansing. The aims of this study were to develop an AI platform which can help patients evaluate the adequacy of bowel cleansing without the aid of caregivers and to investigate whether there was a statistically positive correlation between the Image rating and the BBPS score.
In this study, 200 patients were enrolled from 2023.1.1 to 2023.12.31, and were randomly divided into intervention and control groups. The intervention group compared the effectiveness of intestinal preparation in the two groups with sports drinks as a polyethylene glycol solvent and water as a polyethylene glycol solvent in the intervention group, and compared adverse reactions, acceptability of solution taste, time of oral laxatives, willingness to repeat the same intestinal preparation or the willingness to recommend the same intestinal preparation to others.
This clinical trial is being conducted to assess whether dietary restriction with enteral nutrition prescribed could prevent nonadherence to dietary restrictions, enable additional reduction of the required volume of PEG-ELS.
Sodium picosulfate/magnesium citrate (SPMC) is generally better tolerated than PEG, its cleansing effect remains uncertain. While most studies showed SPMC was non-inferior to PEG, some studies reported that SPMC was less effective than PEG. To improve the bowel cleansing effect of SPMC, splitting the dose by using one sachet the evening before colonoscopy and the other sachet 4 to 5 hours before colonoscopy in the morning, has been proposed.Adding bisacodyl to the regimen also has been shown to be helpful. Some side effects, such as hyponatremia, dehydration and sleep disturbance, were reported to be more commonly associated with SPMC than with PEG. To enhance the efficacy and reduce the side effects, two studies have evaluated the combination of SPMC and PEG, with conflicting results.The effect of combining PEG and SPMC should be best appreciated with head-to-head comparison with PEG and SPMC alone at the same time. Therefore we designed this head-to-head comparison study for 2 L PEG, 1L PEG plus one sachet of SPMC and 2 sachet of SPMC, all with split-dose and the addition of 10 ml bisacodyl. Our hypothesis is the bowel cleansing effect of the combination regimen was not inferior to PEG alone. The tolerability, acceptability and side effects of the 3 regimen will also be evaluated. Patients will be randomly assigned to either PEG, PEG plus SPMC or SPMC group, in a 1:1:1 ratio using a computer-generated sequence. The treatment allocation will be concealed and revealed by non-research medical personnel at the screening visit.
About 30% of patients were reported to suffer inadequate bowel preparation. So, it is desirable to prescribe personalized regimen according to patient's personal characteristics.
Enhanced instructions such as re-education by telephone or short message which increase the patient adherence eventually improve the quality of bowel preparation significantly. However, the effect of family assistance which plays an essential role on compliance of patient with treatment on bowel preparation is unknown. The investigators hypothesized that reinforced education giving family members of outpatients will enhance family support to patients for colonoscopy, and consequently improve the quality of bowel preparation. Therefore, the investigators designed protocols to reinforce family member education by verbal (face to face or telephone) and written methods. The aim of this study is to evaluate the effect of reinforced family member education on patient compliance and the quality of bowel preparation for colonoscopy. In addition，the rate of side effects happening, the subjective feelings of bowel preparation, the outcomes of colonoscopy ,and the independent risk factors will be also assessed.
Objective: The primary objective of this study is to assess the quality of life of people treated with oral phosphate compared with polyethylene glycol + electrolytes to imaging procedures, according to the outcome variables reported by patients. Type of study: A non-interventional observational analytic prospective cohort study. Sample: We will include people who need bowel cleansing for the realization of imaging tests Exposures: - oral sodium phosphate normal regimen - Oral sodium phosphate with modified diet - Polyethylene Glycol + electrolytes Follow-up time: 8 days after the bowel preparation Outcomes: Boston Scale measure Safety Differences between groups in blood test (Sodium, Potassium, Calcium)
Patients intended for ambulatory colonoscopy will be randomized into 2 groups