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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT05667233
Other study ID # 2022-6399
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date February 6, 2023
Est. completion date April 3, 2023

Study information

Verified date August 2023
Source Dalhousie University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

This study aims to investigate if a less physically and psychologically taxing approach to resistance training can generate equal or greater outcomes when compared to a more physically and psychologically taxing approach.


Description:

Resistance training is commonly used to improve body composition, gain strength, increase muscle size (i.e., hypertrophy) and prevent muscle atrophy (i.e., muscle wasting). The most optimal mode of building muscle remains unclear, however there are many mechanisms that can be tested to yield optimal results. One variable that can be manipulated when designing a hypertrophy-focused resistance training regimen is intensity (i.e., proximity-to-failure). Proximity-to-failure is defined as the number of repetitions remaining in a set of prescribed exercises prior to reaching momentary muscular failure (MMF). MMF is when an individual cannot complete the lowering or concentric phase of a given repetition with a full range-of-motion without deviation from the prescribed form of the exercise. For all lifters, particularly amongst older populations, it can be psychologically demanding to push to MMF, and may increase the risk of delayed onset muscle soreness (DOMS) and/or injury due to technical breakdown. In contrast, there is some evidence that suggests training to a slightly less intensity (i.e., within 1-4 repetitions in reserve [RIR]) may result in comparable hypertrophic results with less of a physical and psychological demand on participants. For these reasons, this study looks to investigate if an easier (i.e., less intense) approach to training such as training with repetitions in reserve (RIR), warrants similar or better muscle hypertrophy adaptations to MMF.


Recruitment information / eligibility

Status Completed
Enrollment 13
Est. completion date April 3, 2023
Est. primary completion date March 27, 2023
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Male
Age group 18 Years and older
Eligibility Inclusion Criteria: - biological male - age 18 years or older - enrolled at Dalhousie university - minimum 3-months of consistent (at least 2x/week) resistance training experience Exclusion Criteria: - body fat percentage 25% or greater (obese) - use of performance enhancing drugs that aim to increase rate of muscle growth (i.e., androgenic steroids, anabolic steroids, selective androgen receptive modulators, growth hormone).

Study Design


Related Conditions & MeSH terms


Intervention

Other:
Resistance Training Program
Participants will undergo a high exertion machine-based resistance training protocol.

Locations

Country Name City State
Canada Dalplex Fitness Centre Halifax Nova Scotia

Sponsors (1)

Lead Sponsor Collaborator
Dalhousie University

Country where clinical trial is conducted

Canada, 

Outcome

Type Measure Description Time frame Safety issue
Primary Segment girth (cm) Upper arm (biceps) circumference, mid-thigh (quadriceps) circumference, waist (abdomen) circumference 8-weeks
Secondary Body composition (kg) Fat mass, Fat-free mass, Total Body Mass (fat mass + fat free mass) 8-weeks
Secondary Body Fat Percentage Fat Mass (kg) / Total Body mass (kg) * 100 8-weeks
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