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NCT03514823 Clinical Trial

Respiratory Muscle Contribution to Blood Pressure During Exercise

Blood Pressure Clinical Trial

Official title:
Respiratory Muscle Contribution to Blood Pressure During Exercise in Healthy Humans

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT03514823
Other study ID # 17-011100
Secondary ID 5R01HL126638-03
Status Completed
Phase N/A
First received
Last updated
Start date August 1, 2018
Est. completion date September 25, 2019

Study information
Verified date July 2021
Source Mayo Clinic
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The investigators seek to understand how reflexes from the breathing muscles influence blood pressure during exercise. Furthermore, the investigators are determining if increasing breathing muscle strength (via inspiratory muscle training) influences the respiratory muscle contribution to blood pressure during exercise.

Recruitment information / eligibility
Status Completed
Enrollment 38
Est. completion date September 25, 2019
Est. primary completion date September 25, 2019
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 80 Years
Eligibility Healthy participants with no history of cardiovascular, pulmonary, neurologic, orthopedic or other neuromuscular diseases.

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• Inspiratory Muscle Training (IMT)
Inspiratory muscle training (IMT) are breathing exercises used to increase strength and endurance of the respiratory muscles.
• No Inspiratory Muscle Training (IMT)
No inspiratory muscle training.

Locations
Country Name City State
United States Mayo Clinic Rochester Minnesota

Sponsors (2)
Lead Sponsor Collaborator
Mayo Clinic National Heart, Lung, and Blood Institute (NHLBI)

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary VO2 max test Using a MedGraphics metabolic cart, the investigators will measure the maximum amount of oxygen that an individual can utilize during exercise. During this test the subject will be asked to exercise to his/her max capacity on a recumbent bicycle while breathing through a mouth piece that is hooked into the MedGraphics computer software. Through study completion, an average of one year.
Primary Blood Pressure Blood pressure will be taken every few minutes during exercise testing using a standard blood pressure cuff to monitor changes in blood pressure. Through study completion, an average of one year.
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