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Bipolar Disorder clinical trials

View clinical trials related to Bipolar Disorder.

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NCT ID: NCT00282464 Completed - Bipolar Disorder Clinical Trials

A Six-week Flexible Dose Study Evaluating the Efficacy and Safety of Geodon in Patients With Bipolar I Depression.

Start date: February 2006
Phase: Phase 3
Study type: Interventional

This is a 6-week trial that evaluates the efficacy and safety of Geodon (ziprasidone) in outpatient subjects ages 18 and older with Bipolar Disorder type I, depressed. Subjects are required to undergo a washout period of at least 7 days of any prior med.

NCT ID: NCT00280566 Completed - Bipolar Disorder Clinical Trials

Safety and Maintenance of Effect of Ziprasidone Plus a Mood Stabilizer in Bipolar I Disorder (Manic or Mixed)

Start date: December 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if ziprasidone plus a mood stabilizer will continue to be a safe and effective treatment regimen for adults with Bipolar I Disorder (manic or mixed symptoms) after they have achieved 8 consecutive weeks of symptom improvement on the regimen.

NCT ID: NCT00280293 Completed - Bipolar Disorder Clinical Trials

Lamotrigine add-on Therapy for Bipolar Disorder and Cocaine Dependency

Start date: March 2006
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine if lamotrigine add-on therapy is associated with decreased cocaine craving and improvement in depressive symptom severity than placebo in a group of outpatients with bipolar disorder and cocaine dependence. Additionally, this study is examining whether lamotrigine add-on therapy is associated with decreased cocaine use and the improvement of manic symptom severity than placebo in a group of outpatients with bipolar disorder and cocaine dependence.

NCT ID: NCT00277667 Completed - Bipolar Disorder Clinical Trials

Study of Quetiapine Monotherapy in Ambulatory Bipolar Spectrum Disorder With Moderate-to-Severe Hypomanic Symptoms or Mild Manic Symptoms

Start date: February 2004
Phase: Phase 3
Study type: Interventional

The purpose of this research study is to evaluate the safety, tolerability, and efficacy of quetiapine compared to placebo (sugar pill without medication) in the treatment of bipolar disorder with moderate to severe hypomania or mild mania. Quetiapine is approved by the United States Food and Drug Administration (FDA) for the treatment of schizophrenia and bipolar mania.

NCT ID: NCT00277654 Completed - Bipolar Disorder Clinical Trials

Study of Risperidone Monotherapy in Ambulatory Bipolar Disorder With Concurrent Moderately Severe Anxiety and Lifetime Panic or Generalized Anxiety Disorder

Start date: February 2004
Phase: Phase 3
Study type: Interventional

The purpose of this research study is to evaluate the safety, tolerability, and efficacy (how well the drug works) of risperidone compared to placebo (an inactive drug) in the treatment of bipolar disorder with panic disorder or generalized anxiety disorder. Risperidone is currently approved by the United States Food and Drug Administration (FDA) for the treatment of schizophrenia and bipolar mania. Risperidone is not currently FDA approved for the treatment of bipolar hypomania with or without panic disorder or generalized anxiety disorder (the condition being investigated in this study).

NCT ID: NCT00277212 Completed - Bipolar Disorder Clinical Trials

A Phase IV Study of the Safety and Efficacy of Aripiprazole in Combination With Lamotrigine in the Long-Term Maintenance Treatment of Patients With Bipolar I Disorder With A Recent Manic or Mixed Episode

Start date: December 2005
Phase: Phase 4
Study type: Interventional

Efficacy of Aripiprazole in Combination with Lamotrigine in the Long-Term Maintenance Treatment of Bipolar I Disorder in Outpatients with Recent Manic or Mixed Episode

NCT ID: NCT00276965 Completed - Depression Clinical Trials

Bipolar II Depression: Lithium, SSRI, or the Combination

Start date: September 2006
Phase: Phase 3
Study type: Interventional

This study will compare the safety and effectiveness of a mood stabilizing medication, an antidepressant medication, and a combination of both medications to treat symptoms of bipolar type II depression.

NCT ID: NCT00274677 Completed - Bipolar Disorder Clinical Trials

Depression And Bipolar Disorder

Start date: November 2003
Phase: Phase 3
Study type: Interventional

This study is an 8-week evaluation of an investigational drug for treating depression in bipolar patients. Depressed patients will be given either an investigational drug or placebo and receive psychiatric assessments of their depression at weekly visits. Study drug and all study-related visits are provided at no cost to the patient. The patient agrees to meet with study research staff for roughly 11 clinic visits.

NCT ID: NCT00271258 Completed - Bipolar Disorder Clinical Trials

Safety Study of Sodium Divalproate in Bipolar Disorder in Adolescents

ADOKOT
Start date: January 2005
Phase: Phase 3
Study type: Interventional

- Main objective: To evaluate the clinical and physiological tolerance of sodium divalproate in manic, mixed or hypomanic episodes of bipolar disorder in adolescents treated for 6 months. - Secondary objective: To evaluate the efficacy of sodium divalproate in improving manic, mixed or hypomanic symptoms.

NCT ID: NCT00265330 Completed - Bipolar Disorder Clinical Trials

Safety and Tolerability of Ziprasidone in Children and Adolescents With Bipolar I Disorder (Manic or Mixed)

Start date: March 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the safety and tolerability of ziprasidone during long-term open-label administration in children and adolescents (ages 10-17) with bipolar I disorder (manic or mixed)