Effectiveness of a Hydrophobic Dressing for Microorganisms' Colonization and Infection Control of Vascular Ulcers — CUCO-UV  

Bacterial Infections Clinical Trial

Official title: Effectiveness of a Hydrophobic Dressing for Microorganisms' Colonization and Infection Control of Vascular Ulcers: An Open, Controlled, Randomized Study, With Blinded Endpoint (PROBE Trial): CUCO-UV Study

Status Recruiting

Clinical Trial Summary

This study will determine the effectiveness of CUTIMED® hydrophobic dressings against AQUACEL® silver dressings in bacterial colonization of vascular ulcers.

Clinical Trial Description

Chronic wounds with torpid evolution are a real challenge for health services today. In the case of venous ulcers, it is estimated that more than 80% of these wounds may be colonized or infected by bacteria, which is associated with its chronification by delaying the healing process.

The most widespread therapeutic strategy in routine clinical practice is the use of silver dressings, due to its high antimicrobial power, although the effectiveness of these in venous ulcers is not supported by solid evidence. In addition, there are some uncertainties about the possible adverse effects of systemic absorption of silver molecules, as well as bacterial resistance to silver and the high cost associated with prolonged treatments.

In this sense, a novel method to deal with this problem is the use of dressings with high hydrophobic power, such as CUTIMED®. ;

Related Conditions & MeSH terms

• Bacterial Infections
• Chronic Ulcer of Skin of Lower Limb Nos
• Communicable Diseases
• Infection
• Leg Ulcer
• Ulcer
• Varicose Ulcer
• Venous Leg Ulcer

• NCT number: NCT03667937
• Study type: Interventional
• Source: University of Malaga
• Contact: José Miguel Morales Asencio, PhD
• Phone: 0034951952833
• Email: jmmasen@uma.es
• Status: Recruiting
• Phase: Phase 4
• Start date: May 15, 2019
• Completion date: April 30, 2021