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Bacteremia clinical trials

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NCT ID: NCT00454285 Completed - Bacteremia Clinical Trials

Bacteria Entering the Blood Stream From Tooth Extractions and Tooth Brushing

Start date: January 2003
Phase: Phase 2
Study type: Interventional

The major purposes of this prospective, randomized, clinical study are to: 1. Determine and compare the true incidence, nature, magnitude, and duration (INMD) of bacteremia (bacteria found in the bloodstream) resulting from a highly invasive dental office procedure (tooth extraction) and a minimally invasive and naturally occurring source of bacteremia (tooth brushing); 2. Measure the effect of the American Heart Association's guidelines for amoxicillin prophylaxis (preventive treatment) on the INMD of bacteremia resulting from a single tooth extraction.

NCT ID: NCT00448942 Completed - MRSA Colonization Clinical Trials

The Impact of Chlorhexidine-Based Bathing on Nosocomial Infections

Start date: November 2004
Phase: N/A
Study type: Observational

The purpose of this study was to determine if the use of daily chlorhexidine bathing would decrease the incidence of MRSA and VRE colonization and healthcare associated Bloodstream Infections (BSI) among Intensive Care Unit (ICU) patients.

NCT ID: NCT00435305 Terminated - Pneumonia Clinical Trials

Steady State Serum and Epithelial Lining Fluid (ELF) Antibiotics Concentrations Under Continous Infusion

Start date: November 2006
Phase: Phase 4
Study type: Observational

The purpose of our study is to determine the penetration of continuously infused antibiotics at steady state, mainly Meropenem, Vancomycin, Linezolid, Piperacillin/tazobactam and additionally cefepim and ceftazidim, into epithelial lining fluid.

NCT ID: NCT00428051 Terminated - Sepsis Clinical Trials

Colombia Epidemiologic Surveillance Study

LEAP II
Start date: September 2006
Phase: N/A
Study type: Observational

The study will determine the reduction in invasive pneumococcal disease (IPD) after the introduction of a National Immunization Program with PCV-7 in Bogota. The original LEAP study determine incidence of IPD prior to introduction of PCV-7 in Brazil, Costa Rica and Colombia. LEAP II is the continuation of the study in Colombia only.

NCT ID: NCT00417235 Completed - Bacteremia Clinical Trials

Dressing: Frequency of Change and Evaluation of an Antiseptic-Impregnated Catheter Dressing in ICU Patients

DRESSING
Start date: January 2007
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether a catheter dressing every 7th day is not inferior to a catheter dressing every 3 days and if Chlorhexidine impregnated sponges are effective in preventing catheter-related infections in ICUs.

NCT ID: NCT00414362 Completed - Bacteremia Clinical Trials

Clinical Impact of Fluoroquinolone Resistance in Bacteremia Caused by Gram-Negative Bacilli of Urinary Tract Origin

Start date: February 2007
Phase:
Study type: Observational

The information collected will optimize the management of patients with urinary tract infections with secondary bacteremia, primarily with gram negative bacteria especially Escherichia coli. The current IDSA guideline endorses the use of fluoroquinolones and trimethoprim-sulfamethoxazole as the first line agents. However, over use of this empiric regimen could result in in appropriate treatment of bacteremia.

NCT ID: NCT00414193 Completed - Bacteremia Clinical Trials

Piperacillin/Tazobactam for Bacteremia With Organisms Producing Chromosomally-Encoded AmpC Beta-Lactamase

Start date: February 2007
Phase:
Study type: Observational

Nosocomial bloodstream infections are important causes of morbidity and mortality caused by AmpC beta-lactamase-producing Enterobacteriaceae. The information collected will optimize the management of patients with nosocomial bloodstream infections.

NCT ID: NCT00406198 Completed - Sepsis Clinical Trials

Impact of Continuous Venovenous Haemofiltration on Organ Failure During the Early Phase of Severe Sepsis

Start date: March 1997
Phase: Phase 4
Study type: Interventional

The impact of continuous veno-venous haemofiltration (CVVH) on sepsis-induced multiple organ failure severity is controversial. We thus sought to assess the effect of early application of haemofiltration on the degree of organ dysfunction and plasma cytokine levels in patients with severe sepsis or septic shock.

NCT ID: NCT00404625 Recruiting - Pneumonia Clinical Trials

Infections Caused by ESbL-Producing Enterobacteriaceae in Italy

Start date: October 2006
Phase: N/A
Study type: Observational

To assess the molecular epidemiology, clinical impact, treatment outcome and risk factors for infections caused by Enterobacteriaceae producing ESBLs in Italy in a large multicenter observational survey. SPECIFIC OBJECTIVES 1. To collect consecutive nonreplicate isolates of Enterobacteriaceae resistant to expanded-spectrum cephalosporins from clinical specimens from inpatients and outpatients. 2. To characterize the isolates for resistance phenotypes and for β-lactam resistance mechanisms. 3. To investigate the clonality of isolates. 4. To analyse the epidemiology of various resistance mechanisms/resistant clones. 5. To collect clinical and epidemiological data for patients with infections caused by the ESBL producers. 6. To analyse the epidemiology, risk factors and outcome for infections caused by ESBL producers.

NCT ID: NCT00398411 Completed - Multiple Myeloma Clinical Trials

Moxifloxacin in the Prevention of Bacteremia After High-dose Chemotherapy and Transplantation of Peripheral Stem Cells

MoxiProph
Start date: October 2006
Phase: Phase 3
Study type: Interventional

This study investigates whether the prophylactic use of moxifloxacin during high-dose chemotherapy followed by autologous stem cell transplantation reduces the incidence of clinically significant bacteremia. Further investigations include time to occurrence of fever, duration of fever, overall survival and antibiotic sensitivity of blood isolates.