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Clinical Trial Summary

This is a single center, single arm, open-label phase 1 study to determine the safety and efficacy of autologous T cells expressing CD19 chimeric antigen receptors in adults with CD19+ B cell malignancies.


Clinical Trial Description

This is a single-center, Open Label phase I clinical trial, 9 subjects planned to be enrolled. The subjects will be divided into low-dose group, medium-dose group and high-dose group.Dose CAR+ cells/kg Low 1×105 Medium 2×106 High 6×106 ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03559439
Study type Interventional
Source Shanghai Tong Ren Hospital
Contact Ligen Liu
Phone 18017337037
Email llg3532@shtrhospital.com
Status Recruiting
Phase Phase 1
Start date April 24, 2018
Completion date December 31, 2021

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