Autism Spectrum Disorders Clinical Trial
The purpose of this study is to predict and explain on the basis of brain function and structure the behavioral and brain effects of an evidence-based intervention for adults with high-functioning autism, Virtual Reality-Social Cognition Training (Kandalaft et al., 2012; Journal of Autism and Developmental Disorders). Adults with autism will be randomly assigned to receive either (a) two hours per week of intervention services for five weeks, or (b) a treatment as usual control. The intervention will focus on enhancing social skills, social cognition, and social functioning. Outcome measures will evaluate changes in these social skills, cognition, and functioning using standardized assessments. We will perform structural and functional magnetic resonance imaging (MRI) scans at three time points-before, during, and after treatment (i.e., Time Point #1, 2, and 3).
The purpose of this study is to predict and explain on the basis of brain function and
structure the behavioral and brain effects of an evidence-based intervention for adults with
high-functioning autism, Virtual Reality-Social Cognition Training (Kandalaft et al., 2012;
Journal of Autism and Developmental Disorders). Adults with autism will be randomly assigned
to receive either (a) two hours per week of intervention services for five weeks, or (b) a
treatment as usual control. The intervention will focus on enhancing social skills, social
cognition, and social functioning. Outcome measures will evaluate changes in these social
skills, cognition, and functioning using standardized assessments. We will perform
structural and functional magnetic resonance imaging (MRI) scans at three time points—before
the treatment, after the treatment, and a 3-month follow-up (i.e., Time Point #1, 2, and 3).
All the recruitment will be taking place at Yale Child Study Center (YCSC), while the
intervention will be delivered online by therapists located at the Center for BrainHealth at
the University of Texas at Dallas (UTD). The intervention is called Virtual Reality-Social
Cognition Training (VR-SCT) and has been approved by the IRB at UTD (approval number
#06-54).
;
Allocation: Non-Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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