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Atrial Fibrillation clinical trials

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NCT ID: NCT00580216 Terminated - Atrial Fibrillation Clinical Trials

Evaluation of Weekly Subcutaneous Biotinylated Idraparinux Versus Oral Adjusted-dose Warfarin to Prevent Stroke and Systemic Thromboembolic Events in Patients With Atrial Fibrillation

BOREALIS-AF
Start date: December 2007
Phase: Phase 3
Study type: Interventional

The objective is to evaluate whether once weekly subcutaneous (SC) injection of idrabiotaparinux is at least as efficient to prevent clots in brain and in the other organs than oral international normalized ratio (INR) adjusted-dose warfarin in patients with atrial fibrillation (AF).

NCT ID: NCT00559988 Terminated - Stroke Clinical Trials

Combined Use of BIOTRONIK Home Monitoring and Predefined Anticoagulation to Reduce Stroke Risk

IMPACT
Start date: February 2008
Phase: Phase 4
Study type: Interventional

The IMPACT Study will investigate the potential clinical benefit of the combined use of BIOTRONIK Home Monitoring (HM) technology and a predefined anticoagulation plan compared to conventional device evaluation and physician-directed anticoagulation in patients with implanted dual-chamber defibrillators or cardiac resynchronization therapy devices.

NCT ID: NCT00547794 Terminated - Atrial Fibrillation Clinical Trials

AVJ Ablation Followed by Resynchronization Therapy in Patients With CHF and AF

AVERT-AF
Start date: June 2007
Phase:
Study type: Observational

The purpose of the study is to determine if the combination of AVJ ablation followed by BiV pacing significantly improves functional status and exercise capacity compared to pharmacologic rate control in patients with chronic AF and depressed ejection fraction, regardless of rate or QRS duration.

NCT ID: NCT00528307 Terminated - Atrial Fibrillation Clinical Trials

Changes in Myocardial Perfusion During Chronic Multi Site Biventricular Versus Right Ventricular Apex Pacing in Patients With Normal Left Ventricular Function Undergoing His Bundle Ablation for Drug-refractory Atrial Fibrillation

SOS
Start date: October 2007
Phase: N/A
Study type: Interventional

To determine whether Biventricular pacing in patients undergoing HIS bundle ablation for atrial fibrilation has beneficial effects on myocardial perfusion and left ventricularr ejection fraction.

NCT ID: NCT00519194 Terminated - Atrial Fibrillation Clinical Trials

CONcomitant eValuation of Epicor Left atRial Therapy for AF

CONVERT-AF
Start date: April 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to test the safety and efficacy of the Epicor LP Cardiac Ablation System for treating permanent atrial fibrillation during concomitant open chest and/or open heart surgery for one of more of the following procedures: mitral valve repair or replacement, aortic valve repair or replacement, tricuspid valve repair or replacement, coronary artery bypass surgery or patent foramen ovale (PFO closure).

NCT ID: NCT00477230 Terminated - Atrial Fibrillation Clinical Trials

Pivotal Clinical Study of Endoscopic Ablation for Atrial Fibrillation (AF) in Patients That Have Failed Drugs

ENABLE
Start date: March 2007
Phase: Phase 3
Study type: Interventional

The purpose of the study is to compare two types of treatment for atrial fibrillation (AF) that are designed to treat the symptoms of atrial fibrillation. The treatments being compared are: - A single catheter ablation procedure with the investigational EAS, a visually-guided, light-energy catheter - Standard drug therapy (antiarrhythmic drugs) To learn more about the CardioFocus ENABLE investigational clinical study, please contact the study site closest to you. Eligibility Criteria Persons with paroxysmal atrial fibrillation may be eligible for this study. Other study eligibility criteria include: - 18 to 80 years of age - Frequent episodes of AF - Failed at least 1 drug treatment for AF (beta-blockers or standard AADs) - Other criteria

NCT ID: NCT00442494 Terminated - Atrial Fibrillation Clinical Trials

Corticosteroids for the Prevention of Atrial Fibrillation After Cardiac Surgery

Start date: October 2012
Phase: N/A
Study type: Interventional

Atrial fibrillation is the most common arrhythmia to occur after cardiac surgery. Inflammatory response may be one etiological factor. We hypothesized that intravenous corticosteroid administration after cardiac surgery prevents AF after cardiac surgery.

NCT ID: NCT00437242 Terminated - Atrial Fibrillation Clinical Trials

Odiparcil QT Definitive Study

Start date: October 2006
Phase: Phase 1
Study type: Interventional

This study is being completed to demonstrate the lack of effect of repeat dosing with Odiparcil on the QTc interval.

NCT ID: NCT00415558 Terminated - Atrial Fibrillation Clinical Trials

Prospective Clinical Study of the Guidant Microwave Ablation System for the Treatment of PAF in the MIS Procedure

Start date: May 2007
Phase: N/A
Study type: Interventional

The purpose of this prospective, single-arm, un-blinded, multi-site clinical study is to assess the safety and efficacy of the Microwave Ablation System for the treatment of symptomatic paroxysmal atrial fibrillation (PAF) in the minimally invasive surgical (MIS) procedure in approximately 30 patients at 6 investigational sites in the United States.

NCT ID: NCT00408473 Terminated - Atrial Fibrillation Clinical Trials

Comparative Study of Flecainide CR and Placebo in the Early Treatment of Atrial Fibrillation.

Start date: n/a
Phase: Phase 4
Study type: Interventional

The purpose of the study is to assess the efficacy of flecainide controlled release (CR) in the prevention of recurrent AF during 9 months of active treatment compared to placebo in patients with only one documented AF episode.