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Atopic Dermatitis clinical trials

View clinical trials related to Atopic Dermatitis.

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NCT ID: NCT04525521 Recruiting - Atopic Dermatitis Clinical Trials

Hand Sanitizer Effects on the Skin Barrier

Start date: December 1, 2020
Phase:
Study type: Observational

Hand washing and the use of hand sanitizers are important interventions in disease prevention. Engaging in frequent hand washing is especially effective in preventing the spread of viruses, as this removes microbes and prevents the spread to others. Hand dermatitis, however, is a common occurrence in certain occupations, such as healthcare workers. With the onset of the SARS-CoV2 (COVID-19) pandemic, hand hygiene measures are further enforced as there is no cure or vaccine for this virus. In the study, the effects of hand washing and the use of hand sanitizer on skin proteins and lipids will be assessed.

NCT ID: NCT04520308 Not yet recruiting - Atopic Dermatitis Clinical Trials

An Open-label, Single-arm Longitudinal Study With Dupilumab for Patients With Atopic Dermatitis

Start date: September 1, 2020
Phase: Phase 4
Study type: Interventional

24-week, open-label, single-arm longitudinal study of patients with AD, including a comparison between baseline values for adult patients with moderate-to-severe AD and untreated normal control patients. Patients with AD: ≤24 to 29 weeks, including the screening period Normal control patients: ≤2 days to 5 weeks, including the screening period. Patients with AD: adults with moderate-to-severe AD whose disease cannot be adequately controlled with topical medications or for whom topical treatment is medically inadvisable (eg, intolerance, other important side effects or safety risks) Normal control patients: adults without AD or other atopic disease

NCT ID: NCT04504955 Enrolling by invitation - Atopic Dermatitis Clinical Trials

Corrona Atopic Dermatitis Registry: A Study of Post Approval Drug Safety and Effectiveness

Start date: July 14, 2020
Phase:
Study type: Observational

This prospective, non-interventional research registry is designed to study the comparative effectiveness and comparative safety of approved treatments for patients with atopic dermatitis under the care of a licensed dermatologist or qualified physician extender. Secondary objectives include analyzing the epidemiology and natural history of the disease, its comorbidities, and current treatment practices. Condition or disease : Atopic Dermatitis

NCT ID: NCT04504279 Completed - Atopic Dermatitis Clinical Trials

Evaluation of FB-401 in Children, Adolescents and Adults (2 Years and Older) With Mild to Moderate Atopic Dermatitis

Start date: October 13, 2020
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the potential improvement in atopic dermatitis signs and symptoms following the application of FB-401 in patients 2 years or older with mild to moderate atopic dermatitis. FB-401 will be applied topically for 16 weeks and progress will be assessed by assessment of the skin and patient reports.

NCT ID: NCT04498403 Terminated - Atopic Dermatitis Clinical Trials

A Study of the Long-Term Safety of Crisaborole Ointment, 2% in Japanese Pediatric and Adult Participants With Mild to Moderate Atopic Dermatitis

Start date: September 14, 2020
Phase: Phase 3
Study type: Interventional

This study is a Phase 3, multicenter, open-label, long-term safety extension study of Studies C3291032 and C3291031 in Japanese pediatric and adult participants with mild to moderate Atopic Dermatitis (AD).

NCT ID: NCT04490109 Completed - Atopic Dermatitis Clinical Trials

B244 Topical Spray for the Treatment of Pruritus in Adults With a History of Atopic Dermatitis

Start date: June 4, 2020
Phase: Phase 2
Study type: Interventional

This is a double-blind, randomized, vehicle-controlled study to assess the efficacy, safety, and tolerability of 2 doses of B244 for the treatment of pruritus in adults with a history of atopic dermatitis. Subjects who meet the study entry criteria will be randomized in a 1:1:1 ratio to receive twice daily topical doses of B244 O.D. 5.0, B244 O.D. 20.0, or vehicle (placebo) for 4 weeks.

NCT ID: NCT04486742 Completed - Atopic Dermatitis Clinical Trials

Brief Cognitive Behavioral Therapy to Treat Itch Rumination "Itch CBT" in Eczema

Start date: September 1, 2020
Phase: N/A
Study type: Interventional

The main purpose of this study is to adapt cognitive behavior therapy (CBT) to improve itch in children with eczema.

NCT ID: NCT04476433 Completed - Asthma Clinical Trials

Intervention in Chronic Pediatric Patients and Their Families.

FACTORADAPT
Start date: February 4, 2019
Phase: N/A
Study type: Interventional

This project consists of a psychological intervention in patients and their families with different chronic diseases in order to carry out a comparative study between medical pathologies to know which are the protective or risk variables for the adaptation to the disease.

NCT ID: NCT04472546 Completed - Healthy Clinical Trials

Use of the SpiderMass for in Vivo Analysis of the Skin in Five Chronic Inflammatory Dermatosis

Start date: December 13, 2019
Phase: N/A
Study type: Interventional

The physiological states of the skin are characterized by a certain homeostasis linked to the balance of the metabolic pathways. When these pathways are deregulated, the proteic, lipidic and metabolic is affected. It is thus possible to follow a change in the state of the skin by looking at change in the associated molecular profile. The PRISM laboratory (INSERM U1192) in Lille has developed an innovative system laser called SpiderMass composed of 4 parts: 1. A laser used for the micro-sampling of material in vivo, 2. A transport transfer line of the ablated particles, 3. A mass spectrometer that analyzes them in real time and generates the molecular profiles of the epidermis, 4. A data analysis procedure. The SpiderMass(TM) is of great interest for the study of the skin because it allows non-invasive vivo characterization, and therefore without biopsy or sample preparation. In addition, it will complement techniques already used in the research center such as FTIR spectroscopy. Indeed, in acne studies the FTIR allows to obtain only the Fatty Acid Triglycerid ratio while the SpiderMass permits to detail these lipid classes by each observed molecule on the surface of the skin and follow their evolution.

NCT ID: NCT04468711 Completed - Atopic Dermatitis Clinical Trials

Vitamin D in Egyptian Children With Atopic Dermatitis

Start date: June 6, 2018
Phase: Phase 3
Study type: Interventional

There is an emergent evidence demonstrating the role of Vitamin D deficiency in eczema. Vitamin D supplementation with standard treatment yielded positive clinical outcomes for children and adolescents with mild and moderate AD; however, the potential benefit of vitamin D in severe cases remains unclear