Asthma Clinical Trial
To implement and evaluate a comprehensive asthma education and prevention program in all 54 public elementary schools in the predominantly minority Birmingham, Alabama school system.
BACKGROUND:
The study was part of an initiative "Interventions to Improve Asthma Management and
Prevention at School". The Broad Agency Announcement was released in June, 1994.
DESIGN NARRATIVE:
The study had several objectives. The first was to demonstrate that a comprehensive
school-based asthma education program could be implemented, using existing resources, in a
largely poor, inner city educational environment. The second objective was to provide broad
information on asthma and its management to elementary school faculties in order to help
reduce fear and anxiety due to lack of knowledge about asthma. The third was to provide
curriculum-based information about asthma to the general student bodies of elementary
schools. The fourth objective was to institute a cost effective screening program that would
identify elementary school students with asthma. The fifth was to provide an education
program designed to improve knowledge and prevention. The sixth was to develop an individual
asthma action plan for students with asthma that would improve their management and
prevention skills and to coordinate the individual asthma action plan with school personnel
and activities in order to improve support for the students in following their management
plans.
The program was evaluated through a randomized controlled design with the schools as the
unit of randomization and the students the unit of analysis. The Birmingham public schools
were divided into three cohorts of 18 schools each on the basis of geographic location.
Schools were randomly assigned within cohorts so that nine schools were experimental and
nine were control. The research protocol was implemented in the first cohort in the fall of
1995, in the second cohort in the fall of 1996, and in the third cohort in the fall of 1997.
Students with asthma were followed for three school terms following collection of baseline
data and implementation of the education program. Outcomes were assessed in terms of school
absences and performance, health care utilization, quality of life and asthma morbidity
during school.
;
N/A
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Terminated |
NCT04410523 -
Study of Efficacy and Safety of CSJ117 in Patients With Severe Uncontrolled Asthma
|
Phase 2 | |
| Completed |
NCT04624425 -
Additional Effects of Segmental Breathing In Asthma
|
N/A | |
| Active, not recruiting |
NCT03927820 -
A Pharmacist-Led Intervention to Increase Inhaler Access and Reduce Hospital Readmissions (PILLAR)
|
N/A | |
| Completed |
NCT04617015 -
Defining and Treating Depression-related Asthma
|
Early Phase 1 | |
| Recruiting |
NCT03694158 -
Investigating Dupilumab's Effect in Asthma by Genotype
|
Phase 4 | |
| Terminated |
NCT04946318 -
Study of Safety of CSJ117 in Participants With Moderate to Severe Uncontrolled Asthma
|
Phase 2 | |
| Completed |
NCT04450108 -
Vivatmo Pro™ for Fractional Exhaled Nitric Oxide (FeNO) Monitoring in U.S. Asthmatic Patients
|
N/A | |
| Completed |
NCT03086460 -
A Dose Ranging Study With CHF 1531 in Subjects With Asthma (FLASH)
|
Phase 2 | |
| Completed |
NCT01160224 -
Oral GW766944 (Oral CCR3 Antagonist)
|
Phase 2 | |
| Completed |
NCT03186209 -
Efficacy and Safety Study of Benralizumab in Patients With Uncontrolled Asthma on Medium to High Dose Inhaled Corticosteroid Plus LABA (MIRACLE)
|
Phase 3 | |
| Completed |
NCT02502734 -
Effect of Inhaled Fluticasone Furoate on Short-term Growth in Paediatric Subjects With Asthma
|
Phase 3 | |
| Completed |
NCT01715844 -
L-Citrulline Supplementation Pilot Study for Overweight Late Onset Asthmatics
|
Phase 1 | |
| Terminated |
NCT04993443 -
First-In-Human Study to Evaluate the Safety, Tolerability, Immunogenicity, and Pharmacokinetics of LQ036
|
Phase 1 | |
| Completed |
NCT02787863 -
Clinical and Immunological Efficiency of Bacterial Vaccines at Adult Patients With Bronchopulmonary Pathology
|
Phase 4 | |
| Recruiting |
NCT06033833 -
Long-term Safety and Efficacy Evaluation of Subcutaneous Amlitelimab in Adult Participants With Moderate-to-severe Asthma Who Completed Treatment Period of Previous Amlitelimab Asthma Clinical Study
|
Phase 2 | |
| Completed |
NCT03257995 -
Pharmacodynamics, Safety, Tolerability, and Pharmacokinetics of Two Orally Inhaled Indacaterol Salts in Adult Subjects With Asthma.
|
Phase 2 | |
| Completed |
NCT02212483 -
Clinical Effectiveness and Economical Impact of Medical Indoor Environment Counselors Visiting Homes of Asthma Patients
|
N/A | |
| Recruiting |
NCT04872309 -
MUlti-nuclear MR Imaging Investigation of Respiratory Disease-associated CHanges in Lung Physiology
|
||
| Withdrawn |
NCT01468805 -
Childhood Asthma Reduction Study
|
N/A | |
| Recruiting |
NCT05145894 -
Differentiation of Asthma/COPD Exacerbation and Stable State Using Automated Lung Sound Analysis With LungPass Device
|