Asthma Clinical Trial
Official title:
Airway Dysfunction and Remodelling in Athletes Following Swimming Training in Chlorinated Pools
Swimmers show the highest prevalence of asthma among elite athletes, certainly due to
chlorine exposure. The consequences of a chronic exposure to chlorine compounds by swimmers
and the mechanisms of asthme in this population are still poorly documented. Specific
diagnostic criteria have been proposed by the International Olympic Committee - Medical
Council (IOC-MC) and World anti-doping agency (WADA) to determine the presence of asthma in
athletes. Using the more specific bronchial provocation tests, our aims are
1. to compare the prevalence of asthma in swimmers and control subjects
2. to analyze the Influence of chlorine exposure on bronchial inflammatory processes in
swimmers versus control subjects
3. to study the time-course of changes in airway symptoms, responsiveness, inflammation
and remodeling after cessation of training
n/a
Observational Model: Case Control, Time Perspective: Prospective
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